血中 Malignolipin 証明法による悪性腫瘍の診断

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The authors have applied the malignolipin test, a cancer reaction, devised by pro. Kosaki, to the clinical diagnosis of malignant tumors and have obtained excellent results as follows. The positive rates of the test in cases with gastric cancer was 96.5% (272cases out of 282cases), and in cases with breast cancer it was 97.4% (37 cases out of 38 cases). Furthermore, even in the superficial carcinoma of the stomach, a carcinoma in its early stage, it was as excellent as 92.0% (23 cases out of 25 cases). On the other hand it was only 9.3% (10 cases out of 108 cases) in normal persons, then the test was used as a screening filter of the gastric-mass-survey, and one case of gastric cancer, who had no subjective complaint, was detected among 969 examinees. Next, the follow-up results of the patients after the gastrectomy for gastric carcinoma suggested that this method can be used for the early detection of the cancer recurrence or for the estimation of prognosis after the operation. Recently the authors have examined with this test the subjects with diseases of the oral region. The positive rate of the test was 92.4% (24 cases out of 26 cases) in the maligant tumors (maxillar carcinoma 6, mandibular carcinoma 6, lingual carcinoma 10, buccal carcinoma 3, and carcinoma of the floor of mouth 1), 25.0% (2 cases out of 8 cases) in the benign tumors, and 9.1% (1 case out of 11 cases) in the control group. After the radical removal of the malignant tumors the test turned negative in 6 months in 5 cases ; another 2 cases, who kept positive also postoperatively, died of recurrence. The facts indicate that the test is excellent as a clinical detection of malignant tumors.
九州歯科学会の論文
1967-09-30

血中 Malignolipin 証明法による悪性腫瘍の診断

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