コバルト内標準法を用いる誘導結合プラズマ質量分析法による血清中の微量ガリウムの定量

概要

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A method for the determination of gallium at the μg dm^<-3> level by ICP-MS was studied as a basis for serum analysis. Coexisting NaCl (>0.01%) markedly reduces the ion intensities of ^<69>Ga and ^<71>Ga, whereas glucose (0.01〜0.1%) does not interfere with the determination. Cobalt was found to be effective as an internal standard element, so as to correct for any matrix interference from NaCl. The method was applied to analyses of 1000- to 10- fold diluted serum samples spiked with Ga. The polyatomic ion (^<37>Cl^<16>O_2) interference with the ^<69>Ga intensity became significant when 10-fold diluted serum was analyzed. Therefore, a measurement of the ion intensity at ^<71>Ga was preferred in order to obtain reliable results.
社団法人日本分析化学会の論文
1998-01-05