老若動物における赤血球の態度とビタミンEの影響 : (I)溶血反応および血漿TBA値に及ぼす加令の影響とビタミンEの效果

概要

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On red blood cells obtained from rats fed by commercial NMF diet, it was observed that the hemolysis in the hypotonic salt solution was intensified with the progress of aging. However the hemolysis by dialuric acid was not affected with age. Similar experiment was carried out by using a synthetic diet for examine the effect of tocopherol. It was observed that the hemolytic behavior in the hypotonic salt solution was normal in any experimental animal fed by E-supplemented diets, and the hemolysis by dialuric acid was intensified with E deficiency in any rat. TBA values of the sedimented portion of plasma in these rats were determined. It was observed as a rule that the increasing TBA values were found in the rats which showed intensified hemolysis of the red blood cells in the hypotonic salt solution. These results suggested that (1) the commercial diet was inferior to the synthetic diet and might be scanty in E and/or Some other nutrient, (2) the hemolysis in the hypotonic salt solution was not always parallel to the hemolytic behavior by dialuric acid, (3) the change of the hemolytic behavior by aging might be related to complicated environments.
日本ビタミン学会の論文
1970-11-25