ビタミンD代謝機構にかんする研究 : (IV)"活性硫酸塩"代謝径路にたいするビタミンDの効果

概要

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White Leghorn chicks were fed with vitamin D-deficient diet with the addition of vitamin D_3 or D_3. In the group receiving vitamin D_3,the increase in citrate oxidizing ability in liver homogenate was statistically significant, while no influence was found on oxidative phosphorylating ability of citric acid. The convertion of inorganic phosphate to organic phosphorus compound was increased by the administration of vitamin D_3. It suggests that there may be some relation between phosphorus and sulphur metabolisms. No influence was observed on the pyruvate oxidative phosphorylating ability and pyruvate oxidase in liver homogenate, by the administration of vitamin D_3. With regard to the high level of "active sulfate", the increase of reduced glutathione in blood was statistically significant in the group receiving vitamin D_3,but no influence was observed on oxidized glutathione in blood and liver. The above results suggest that SH-group may be able to supply osseomucoid with sulphur.
日本ビタミン学会の論文
1962-11-25