L-グルタミン酸生産菌Brevibacterium sp.No.6菌の安息香酸の代謝経路について (微生物による芳香族化合物からのアミノ酸の生産-1〜3-〔英文〕)

概要

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The metabolic pathway of benzoate in Brevibacterium sp. No.6,a typical glutamate producer, was studied. The benzoate-grown cells showed strong oxidation activity for benzoate and catechol, and weak activity for m- and p-hydroxybenzoate, protocatechuate, and gentisate. It was thus estimated that benzoate was metabolized first to catechol. cis, cis-Muconate and β-ketoadipate were confirmed as the products from catechol in the reaction with a cell-free extract of the benzoate-grown cells. Equimolar conversion of catechol to β-ketoadipate was shown by stoichiometric analyses. The metabolic pathway inferred is : Benzoate→Catechol→cis, cis-Muconate→β-Ketoadipate.
公益社団法人日本生物工学会の論文
1972-12-25