高α-リノレン酸投与正常および担がんマウスの血清多価不飽和脂肪酸に及ぼす鉄, ビタミンCおよびE添加の影響

概要

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The effect of supplement of a high amount of α-linolenic acid and further iron (II) and vitamins C and E on the serum polyunsaturated fatty acid levels was investigated in normal and Ehfiich's ascites tumor-bearing mice. The serum levels of arachidonic acid (AA) decreased and eicosapentaenoic acid (EPA) increased in both normal and tumor-bearing mice by the supplement of α-linolenic acid. In normal mice, docosahexaenoic acid (DHA) was not changed by these supplements, but it decreased in tumor-bearing mice. The ratio of EPA/AA increased by supplement of α-linolenic acid and further increased by the addition of iron (II) and vitamins C and E. The serum polyunsaturated fatty acid compositions were changed significantly by the simultaneous supplement of vitamins C and E, but not by the addition of either of vitamin C or vitamin E.
日本ビタミン学会の論文
1999-01-23