芳香族アルコールまたはp-ニトロフェノールによる清酒酵母の呼吸欠損変異誘発に及ぼす脂肪族アルコールの影響

概要

論文の詳細を見る
We previously repoerted thant aromatic alcohols with a hydroxy group in the α-position of a side chain were highly effective in inducing respiratory-deficiency in Saccharomyces sake.This paper deals with the effect of aliphatic alcohols (C_1-C_4) on the induction of respiratory-deficient mutants by aromatic alcohols (C_7-C_<10>) or p-nitrophenol. At high concentration, the aliphatic alcohols other than methanol prevented almost completely the induction of respiratory-deficiency even though they are themselves mutagenic in the absence of aromatic alcohols. In contrast, at lower concentrations, some of the aliphatic alcohols promoted induction of respiratory-deficiency by the aromatic alcohols.p-Nitrophenol-induced respiratory-deficiency was depressed by addition of methanl, ethanol, n-propanol, iso-propanol and n-butanol but not affected by iso-, sec- and tert-butanols.The mechanism of this effect of aliphatic alcohols remains to be elucidated.
社団法人日本生物工学会の論文