PEG-Inhibitor Conjugates : Application of Diphenyl α-Aminoalkylphosphonate to Removal of Chymotrypsin(Biochemistry & Molecular Biology)

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概要

• 論文の詳細を見る

• Diphenyl 1-amino-2-phenylethylphosphonate was introduced to poly(ethylene glycol)s (PEGs) with average molecular masses of 300, 400, and 600 to prepare water-insoluble PEG-inhibitor conjugates. Interestingly, only the conjugate from PEG with an average molecular weight of 600 formed a precipitate with chymotrypsin but not with trypsin. The results demonstrated that the PEG-inhibitor conjugate is useful for separation of chymotrypsin.

• 社団法人日本農芸化学会の論文
• 2003-10-23

著者

• Ono Shin

  Department of Radiology, School of Veterinary Medicine, Azabu University

• 吉村 徹

  Institute For Chemical Research Kyoto University

• UMEZAKI Makiko

  Department of System Engineering of Materials and Life Science, Faculty of Engineering, Toyama Unive

• YOSHIMURA Toshiaki

  Department of System Engineering of Materials and Life Science, Faculty of Engineering, Toyama Unive

• FUJII Takayoshi

  Department of Material Systems Engineering and Life Science, Faculty of Engineering, Toyama Universi

• YAMAZAKI Isao

  Yayoi Kagaku Kogyo Co., Ltd.

• Yoshimura T

  Institute For Chemical Research Kyoto University

• Ono S

  Department Of System Engineering Of Materials And Life Science Faculty Of Engineering Toyama Univers

• Ono S

  Toyama Univ. Toyama Jpn

• Yoshimura Tohru

  (present Adress)institute For Chemical Research. Kyoto University

• Yamaura I

  Yayoi Kagaku Kogyo Co. Ltd.

• Yamazaki Isao

  Yayoi Kagaku Kogyo Co. Ltd. Fukuoka-machi

• Umezaki Makiko

  Department Of System Engineering Of Materials And Life Science Faculty Of Engineering Toyama Univers

• Umezaki Makiko

  Department Of Chemical And Biochemical Engineering Faculty Of Engineering Toyama University

• Fujii Takayoshi

  Department Of System Engineering Of Materials And Life Science Faculty Of Engineering Toyama Univers

• Fujii Takayoshi

  Department Of Chemistry University Of Tsukuba

• Fujii Takayoshi

  Department Of Applied Molecular Chemistry College Of Industrial Technology Nihon University

• Yamaura I

  Department Of Applied Microbial Technology The Kumamoto Institute Of Technology

• Ono Shin

  Department Of Chemical And Biochemical Engineering Faculty Of Engineering Toyama University

• Yoshimura Toshiaki

  Department of Applied Chemistry, Faculty of Engineering, Osaka City University

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