Biosynthetic Relationship between Acutumine and Dechloroacutumine in Menispermum dauricum Root Cultures

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概要

• 論文の詳細を見る

• The biosynthetic relationship between acutumine 1 and dechloroacutumine 2 was studied using ^<13>C-labeled tyrosine and ^3H-labeled 2 as tracers. ^<13>C-NMR spectra of ^<13>C-labeled 1 and 2 showed that the alkaloids, each composed of two molecules of tyrosine, are derived from the same biosynthetic pathway. Feeding Menispermum dauricum (Menispermaceae) roots, cultured in a chloride-enriched medium, with ^3H-labeled 2 demonstrated that 1 is the only alkaloid metabolite of 2. Conversion (5%) of the exogenously applied 2,taken up by the roots, into 1 showed that 2 is the precursor of 1. Incomplete conversion of 2 into 1 suggests accumulation of the exogenously applied 2 in cell organelles and/or compartmentation of the enzymes involved in the biosynthesis of 1.

• 社団法人日本農芸化学会の論文
• 1999-03-23

著者

• ISOGAI Akira

  Graduate School of Agricultural and Life Sciences, The University of Tokyo

• Sugimoto Yukihiro

  Arid Land Research Center, Tottori Univ.

• Sugimoto Yukihiro

  Arid Land Research Center Tottori Univ.

• Isogai A

  Graduate School Of Biological Sciences Nara Inst. Of Sci. And Technol.

• Isogai Akira

  Graduate School Of Biological Science Nara Institute Of Science And Technology

• Isogai Akira

  Graduate School Of Agricultural And Life Sciences The University Of Tokyo

• INANAGA Shinobu

  Arid Land Research Center, Tottori University

• BABIKER HindA.A.

  Arid Land Research Center, Tottori University

• SAISHO Tomoki

  Arid Land Research Center, Tottori University

• HASHIMOTO Masayuki

  Nitto Technical Information Center Co., Ltd.

• Inanaga S

  Tottori Univ.

• Inanaga Shinobu

  Arid Land Res. Center Tottori Univ.

• Hashimoto M

  Kddi R&d Laboratories Inc.

• Saisho Tomoki

  Arid Land Research Center Tottori University

• Sugimoto Y

  Tottori Univ. Tottori Jpn

• Yamamoto S

  Department Of Bioengineering Tokyo Institute Of Technology

• Babiker Hinda.a.

  Arid Land Research Center Tottori University

• Inanaga S

  Arid Land Research Center Tottori University

• Isogai Akira

  Graduate School Of Agricultural And Life Science The University Of Tokyo

• Babiker Hind

  Arid Land Research Center, Tottori University

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