Age-related Changes in Glutathione Concentration, Glutathione Peroxidase, Glutathione-S-Transferase, and Superoxide Dismutase Activities in Senescence Accelerated Mice
スポンサーリンク
概要
- 論文の詳細を見る
Age-associated changes in several antioxidative factors were studied in blood and liver from mice prone to accelerated senescence aged 0. 7 to 1. 4 years and mice resistant to accelerated senescence aged 1. 0 to 2. 1 years. In both strains, activities of hepatic glutathione peroxidase (GSH-Px) and glutathione-S-transferase (GST) decreased significantly with age, and the activity of superoxide dismutase (SOD), and the concentration of glutathione (GSH) in liver and blood cells tended to decrease with age. The GSH concentration in the plasma and blood cells, and the hepatic GST and SOD activities were significantly lower in the mice prone to senescence than other strain, but the hepatic GSH concentration and GSH-Px activity were similar in the two strains. These results suggest that GSH and hepatic antioxidative enzymes are associated to some extent with senescence in mice with accelerated senescence.
- 社団法人日本農芸化学会の論文
- 1994-06-23
著者
-
HE Puming
Department of Applied Biological Chemistry, Faculty of Agriculture, Shizuoka University
-
He P
Shizuoka Univ. Shizuoka Jpn
-
He Puming
Research Institute for Food Science, Kyoto University
-
Yamaoka-Koseki Sakiyo
Research Institute for Food Science, Kyoto University
-
Yasumoto Kyoden
Research Institute for Food Science, Kyoto University
-
Yasumoto K
Department Of Food And Nutrition School Of Life Studies Sugiyama Jogakuen University
-
Yasumoto Kyoden
Research Institute For Food Science Kyoto University
-
Yamaoka-koseki Sakiyo
Research Institute For Food Science Kyoto University
関連論文
- Elevated Urinary Cr Loss Induces a Reduction in Renal Cr Concentration and the Negative Cr Balance in Streptozotocin-Induced Diabetic Mice
- Glycosidic Flavonoids as Rat-Liver Injury Preventing Compounds from Green Tea
- Suppression of D-Galactosamine-Induced Rat Liver Injury by Glycosidic Flavonoids-Rich Fraction from Green Tea
- Age-related Changes in Glutathione Concentration, Glutathione Peroxidase, Glutathione-S-Transferase, and Superoxide Dismutase Activities in Senescence Accelerated Mice
- Effect of Paraquat Administration on Antioxidative Enzyme Activities and Oxidative Damage in the Blood and Liver of Senescence-accelerated Mice
- Role of the Carbohydrate Chain and Two Phosphate Moieties in the Heat-Induced Aggregation of Hen Ovalbumin
- Linear Polymerization Caused by the Defective Folding of a Non-Inhibitory Serpin Ovalbumin
- Comparative Effect of Dietary Olive, Safflower, and Linseed Oils on Spontaneous Liver Tumorigenesis in C3H/He Mice
- Reductive Effect of Hot-Water Extracts from Woody Ear (Auricularia auricula-judae Quel.) on Food Intake and Blood Glucose Concentration in Genetically Diabetic KK-A^y Mice
- Hypoglycemic Effect of a Hot-water Extract from Defatted Sesame (Sesamum indicum L.) Seed on the Blood Glucose Level in Genetically Diabetic KK-A^y Mice(Food & Nutrition Science)
- Suppressive Effect of Coffee on Lipopolysaccharide-induced Hepatitis in D-Galactosamine-sensitized Rats(Food & Nutrition Science)
- Suppressive Effect of Caffeine on Hepatitis and Apoptosis Induced by Tumor Necrosis Factor-α, but Not by the Anti-Fas Antibody, in Mice
- Suppression of Lipopolysaccharide-induced Liver Injury by Various Types of Tea and Coffee in D-Galactosamine-sensitized Rats
- Green Tea Suppresses D-Galactosamine-Induced Liver Injury in Rats
- Improved Swimming Pool Achieves Higher Reproducibility and Sensitivity to Effect of Food Components as Ergogenic Aids
- Suppression of D-Galactosamine-induced Liver Injury by Mushrooms in Rats
- Amino Acid Composition of Soybean Protein Increased Postprandial Carbohydrate Oxidation in Diabetic Mice(Food & Nutrition Sience)
- Use of ^C-labeled Glucose for Measuring Exogenous Glucose Oxidation in Mice(Food & Nutrition Science)
- Zinc Bioavailability Is Improved by the Micronised Dispersion of Zinc Oxide with the Addition of L-Histidine in Zinc-Deficient Rats
- Histological Study of Iron Deposits in Selenium-deficient Rats
- Selenium Deficiency as a Cause of Overload of Iron and Unbalanced Distribution of Other Minerals
- Induction after Administering Paraquat of Heme Oxygenase-1 and Heat Shock Protein 70 in the Liver of Senescence-accelerated Mice
- Hypoglycemic Effect of Water-soluble Polysaccharide from Auricularia auricula-judae Quel. on Genetically Diabetic KK-A^y Mice
- Near-Infrared Diffuse Reflectance Spectroscopic Analysis of the Amounts of Moisture, Protein, Starch, Amylose, and Tannin in Buckwheat Flours
- Preservative Effect of Polyols on the Stability of Biocatalysts during Short-term Dehydration Stress
- Ameliorating Effects of Water-Soluble Polysaccharides from Woody Ear (Auricularia auricula-judge Quel.) in Genetically Diabetic KK-Ay Mice
- Endogenous Factors Responsible for the Textural Characteristics of Buckwheat Products
- Effects of Inorganic Salts and Phytate on Gelling Properties of the Seaweed Amikusa (Ceramium boydenii)
- Determination of Palmitic Acid, Oleic Acid and Linoleic Acid by Near-Infrared Transflectance Spectroscopy in Edible Oils.
- Effects of Houttuyniae cordata and Refinery Final Molasses on the Development of Offensive Odor in Porcine Small Intestine during Storage.
- Effect of Ingestion of Excess Methionine Diet on Aging of Erythrocytes in Mice.
- Effects of Sugars and Aspartame on the Uptake and Transport of Iron by Caco-2 Cells Cultured in Serum-Free Medium.
- Hemoglobin Replection and the Hematological Response of Anemic Rats to Hemosiderin and Ferrous Sulfate.
- Effects of Amino Acids and Dipeptides on the Uptake and Transport of Iron by Caco-2 Cells Cultured in Serum-Free Medium.