Identification of a Novel 8-0xoguanine-DNA Glycosylase Activity of Escherichia coli Endonuclease III to Prevent Spontaneous G:C-C:G Transversions

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概要

• 論文の詳細を見る
• 日本放射線影響学会の論文

著者

• Zhang Q‐m

  Laboratory Of Radiation Biology Graduate School Of Science Kyoto University

• Zhang Q‐m

  Department Of Biological Sciences Graduate School Of Science Kyoto University

• YASUI Akira

  Inst. Dev. Aging Cancer, Tohoku Univ.

• Yasui Akira

  Idac Tohoku Univ.

• Yasui Akira

  Inst. Dev. Aging Cancer Tohoku Univ.

• Yamamoto Kazuo

  Graduate School Of Life Sciences Tohoku Univ.

• TAKAO Masashi

  Inst. Development, Aging and Cancer, Tohoku Univ.

• TAKAO Masashi

  IDAC Tohoku Univ.

• ZHANG Qiu-Mei

  Labo. Radiat. Biol., Kyoto Univ.

• YONEI Shuji

  Labo. Radiat. Biol., Kyoto Univ.

• MATSUMOTO Yukiko

  Labo. radiat. Biol., Kyoto Univ.

• YAMAMOTO Kazuo

  Dept. Biol., Tohoku Univ.

• Matsumoto Yukiko

  Radiat. Biol. Kyoto Univ.

• Matsumoto Yoshihisa

  Research Laboratory For Nuclear Reactors Tokyo Institute Of Technology

• Matsumoto Yoshihisa

  Res. Lab. For Nuclear Reactors And Dep. Of Nuclear Engineering Tokyo Inst. Of Technol.

• Yonei S

  Department Of Biological Sciences Graduate School Of Science Kyoto University

• Yonei Shuji

  Labo. Radiat. Biol. Grad. Sch. Sci. Kyoto Univ.

• Qiu-mei Zhang

  Kyoto Univ. Fac. Of Sci.

• Takao Masashi

  Inst. Development Aging And Cancer Tohoku Univ.

• Zhang Qiu-mei

  Labo. Radiat. Biol. Grad. Sch. Sci. Kyoto Univ.

• Zhang Qiu-mei

  Lab. Of Radiat. Biol. Graduate School Of Science.

• Matsumoto Yoshihisa

  Atomic Bomb Disease Institute Graduate School Of Biochemical Sciences Nagasaki University

関連論文

• 88 Excessive Base Excision Repair of Clustered DNA Damage by E. coli MutM and human Ogg1 Causes Enhanced Sensitivity to Low LET radiation in E. coli(Repair of radiation damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Identification of Repair Enzymes for 5-Formyluracil in DNA : Endonuclease III, Endonuclease VIII and MutM Proteins of Escherichia coli
• Role of DNA Double-strand Break Repair Genes in Cell Proliferation under Low Dose-rate Irradiation Conditions
• The Shizosaccharomyces pombe Homolog (SpMYH) of the Escherichia coli MutY Is Required for Removal of Guanine from 8-Oxoguanine/Guanine Mispairs to Prevent G:C to C:G Transversions
• Identification of 8-oxoguanine-DNA Glycosylase/AP Lyase Activity in Extracts from Schizosaccharomyces pombe
• Disruption of the Schizosaccharomyces pombe homolog of MutY (SpMYH).
• Isolation and Characterization of SpMYH, a MutY Homolog, of Fission Yeast Schizosaccharomyces Pombe
• Response of osteoblasts and osteoclasts in regenerating scales to gravity loading
• Screening of Regulatory Region of Fish Photolyase Gene.
• DNA Synthesis by Escherichia coli DNA Polymerase IV (DinB) on Templates Containing Oxidized Bases
• 170 Hyperthermic radiosensitization of chicken Blymphocyte DT40 and Its derivatives laking NHEJ and/or HR pathways of DNA DSBrepair(Radio-protection and sensitization, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 90 Role of DNA-dependent protein kinase in initial recognition of DNA double-strand breaks(Repair of radiation damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Effect of wortmannin on radiation-induced apoptosis
• 131 Effects of the Strong Static Magnetic Field on the Expression of Proto-oncogenes in HL-60 Cells(Effects of electro-magnetic fields, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Exposure to Storng Static Magnetic Field Enhances Production of Superoxide Radicals in E. coli
• dentification of Repair Enzymes Recognizing 7,8-Dihydro-8-oxo-guanine Opposite Guanine or Adenine in Escherichia coil
• Cloning and Characterization of Caenorhabditis elegans Gcnes That Correct Hydrogen Peroxide Sensitivity of E. coli oxyR Mutant
• 169 Effects of hyperthermia on DNA-PK activity and radiosensitivity(Radio-protection and sensitization, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Cellular responses and repair of single-strand breaks introduced by UV damage endonuclease in mammalian cells
• Alternative Splicing of Human DNA Glycosylases and IR Response
• Expression of CPD and 64 photolyase Genes in Human Cells
• Cloning and characterization of photolyase homolog from mouse
• 208 DNA repair function and structural modeling of a putative DNA glycosylase NEIL3(Physics, chemistry and DNA damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Identification of a DNA Glycosylase Activity of Human hNTH1 Protein Acting on 5-Formyluracil, a Major Oxidative Lesion of Thymine
• Free Radical Scavenger Edaravone Suppresses X-ray-induced Apoptosis through p53 Inhibition in MOLT-4 Cells
• Identification of a JNK form induced by X-irradiation during apoptosis
• 250 Mechanism of inhibitory effect of vanadate on apoptosis(Apoptosis related, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Phosphorylation of XRCC4 by DNA-dependent protein kinase : an in vitro study using purified proteins
• Decreased expression of c-Myc in X-ray-induced apoptotic cell death of human T-cell leukemia cell lineMOLT-4
• The Substrates in vivo of DNA-dependent Protein Kinase : XRCC4 as a Candidate
• Heat Stability of DNA-PK and Hyperthermic Radiosensitization in Mammalian Cell Lines
• Phosphorothioate Oligonucleotides as Inhibitors of DNA-dependent Protein Kinase Activity
• p41 Is a Cleavage Product from Oncoprotein SETβ by Caspase(s) in Radiation-induced MOLT-4 Cell Death
• Acidic sphingomyelinase inhibitor - D609 protects U937 cells from heatinduced apoptosis
• Involvement of SAPK/JNK pathway in X-ray-induced apoptosis of human T-cell leukemia cell line MOLT-4
• Wortmannin Enhanced X-ray-induced Cell Death in MOLT-4 Cells
• Sensitization by Wortmannin of Heat- or X-ray Induced Cell Death in Cultured Chinese Hamster V79 Cells
• A Gel-electrophoretic Analysis for Improved Sensitivity and Specificity of DNA-dependent Protein Kinase Activity
• Identification of a Novel 8-0xoguanine-DNA Glycosylase Activity of Escherichia coli Endonuclease III to Prevent Spontaneous G:C-C:G Transversions
• Effects of Thioredoxin and Glutaredoxin Systems on Regulation of Superoxide Stress Responses in Escherchia coli
• The Effect of 5-Formyluracil, a Major Oxidative Lesion of Thymine, on Biological Function of DNA in vivo and in vitro
• Purification and Characterization of C-C Mismatch-Binding Proteins in Escherichia coli
• Identification of 7,8-Dihydro-8-oxoguanine-DNA Glycosylase Activity of Caenorhabditis elegans
• Regulation of Oxidative Stress Responses by Redox Enzymes in Escherichia coli
• 3'-Blocking Damage of DNA as a Mutagenic Lesion Caused by Hydrogen Peroxide in Escherichia coli
• The Effect of 5-Formyluracil and 5-Hydroxymethyluracil, a Major Oxidative Lesion of Thymine, on Biological Functions of DNA
• Purification and Characterization of C-C Mismatch-binding Proteins in Escherichia coli
• The Escherichia coli HU Protein Regulates DNA Repair through RecA-Dependent and Independent Pathways
• Redox Regulation of Oxidative Stress Responses in Escherichia coli
• Identification and Purification of C-C Mismatch-Binding Protein in Extracts of Escherichia coli
• Roles of the SoxRS Regulon in Spontaneous and Menadione-Induced Reversion to Lac+ in Escherichia coli
• Redox Regulation of Hydrogen Peroxide Stress Response in Escherichia coli
• Induction of Repair Capacity for Oxidatively Damaged DNA as a Component of Peroxide Stress Response in Escherichia coli
• Identification of DNA Damage Causing GC-CG Transversion by Radiation and Its Protective Systems in Escherichia Coli
• Identification of G-G and C-C Mismatch-Binding Activities in Extrads of Schizosaccharomyces Pombe and Escherichia Coli
• Isolation and Characterization of Escherichia coli Mutant That Shows High Frequency of Spontaneous GC-CG transversion
• 4-NQO-Induced Mutations in the lacZ Gene and Repair Pathways in Stationary Phase of Eschericida coli
• Generation, Biological Consequences and Repair Mechanisms of Cytosine Deamination in DNA
• Purification and Characterization of 5-Formyluracil DNA Glycosylase from Human Cells in Culture
• Recombinant Schizosaccharomyces pombe Nth1 Protein Exhibits DNA Glycosylase Activities for 8-oxo-7,8-dihydroguanine and Thymine Residues Oxidized in the Methyl Group
• Identification of Eukaryotic Homologues of Escherichia coil MutY Protein
• Multiple Pathways of Repair for 7,8-Dihydro-8-oxoguanine:C, A, G Mispairs in Escherichia coli
• Analysis of Reapir Pathways for C-C Mismatch in DNA in Escherichia coil
• 218 Overexpression of hOGG1 protein enhanced the sensitivity to killing by gamma-rays in HeLa cells(Physics, chemistry and DNA damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 102 Purification and Characterization of Schizosaccharomyces pombe Nth Homologue(Repair of radiation damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 101 Identification of Caenorabditis elegans Repair Enzymes for Oxidative Base Damage in DNA(Repair of radiation damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 92 Phenotypic Assay of C. elegans Deficient in Uracil DNA Glycosylase Activity(Repair of radiation damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Effects of Redox Enymes on Regulation of Oxidative Stress Responses in Fscherchia coil
• 5-Formyluracil, a Major Product of Thymine Oxidation, Induces Base Substitutions and Deletions on a Plasmid Replicated in Escherichia coli
• Identification of Human Nei Protein as a 5-Formyluracil DNA Glycosylase/AP lyase
• Purification and Characterization of Schizosaccharomyces pombe Nth Homologue
• Phenotypic Properties of C. elegans Defective in Uracil-DNA Glycosylase Activity
• DNA Glycosylases in Base Excision Repair Systems : Specificity and Roles in Prevention of Mutations
• Identification of Binding Activities to 8-Oxoguanine-Containing Oligonucleotides in Extracts Prepared fromSaccharomyces cerevisiae
• Cloning and Characterization of Uracil-DNA Glycosylase Gene of Caenorhabditis elegans
• Identification of 5-Hydroxymethyluracil-DNA Glycosylase Activities in Extracts from Escherichia coli
• 143 The functional characterization of Nth homologue in hyperthermophilic archaeon Pyrococcus horikoshii OT3(Redox regulation, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Implication of iron in spontaneous mutagenesis in E. coli mutants lacking reactive oxygen species (ROS) scavenging enzymes.
• Enzymatic Repair Mechanisms for Base Modifications Induced by Oxygen Radicals
• A gel electrophoretic assay for increased sensitivity of DNA-PK activity
• DNA-dependent protein kinase activity of ataxia telangiectasia-and X-linked agammaglobulinemia-derived cells.
• Identification and Characterization of a Protein Found After X-Irradiation in Human T Cell Leukemia
• Effect of Wortmannin on the Heat-Induced Cell Death in V79 cells
• Molecular Mechanisms for Transcriptional Regulation of Escherichia coli Endonuclease VIII gene (nei)
• Identification of Caenorhabditis elegans Genes That Complement Hydrogen Peroxide Sensitivity of oxyR Mutant of Escherichia coli
• Molecular property and function of DNA-PK - Hyperthermic lability of DNA-PK and hyperthermic radiosensitization -
• 108 Property of novel mouse Thymine Glycol-DNA Glycosylase(Repair of radiation damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Purification of Novel Mouse Thymine Glycol-DNA Glycosylase
• Novel Thymine Glycol Glycosylase Activitv in Mouse Nuclear Extract
• dentification of 5-Formyluracil DNA Glycosylase/AP Lyase Activity of S. cerevisiae Ntg1 and Ntg2 Proteins
• Replication of DNA Templates Containing the 5-Formyluracil, a Major Oxidative Lesion of Thymine in DNA
• Identification of Adenine-DNA Glycosylase Activity in Extracts Prepared from Saccharomyces cerevisiae
• Ability to repair DNA double-strand breaks related to cancer susceptibility and radiosensitivity
• Clinical Studies of Immunohistochemical Staining of DNA-dependent Protein Kinase in Oropharyngeal and Hypopharyngeal Carcinomas
• Gene Expression Associated with DNA-Dependent Protein Kinase Activity under Normoxia, Hypoxia, and Reoxygenation
• Deletion and Frameshift Mutations; Maintaining the Genetic Stability
• The Roles of DNA Polymerase I in Chromosome Instability in Escherichia coli
• Role of oxidative stress defense system on genotoxicity and cytotoxicity of aldehydes. : Implication of glutathione
• Comparison of Effect of Sodium Hydroxide on the Decomposition of 2-Chlorophenol and Phenol in Supercritical Water and at Supercritical Water Oxidation Conditions
• Gimeracil, an inhibitor of dihydropyrimidine dehydrogenase, inhibits the early step in homologous recombination

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