88 Excessive Base Excision Repair of Clustered DNA Damage by E. coli MutM and human Ogg1 Causes Enhanced Sensitivity to Low LET radiation in E. coli(Repair of radiation damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)

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概要

• 論文の詳細を見る
• 2003-12-15

著者

• Zhang Q‐m

  Laboratory Of Radiation Biology Graduate School Of Science Kyoto University

• Zhang Q‐m

  Department Of Biological Sciences Graduate School Of Science Kyoto University

• YONEI Shuji

  Radiat. Biol. Grad. Sch. Sci. Kyoto Univ.

• CHANG Po

  Lab. Radiat. Biol., Grad. Sch. Sci., Kyoto Univ.

• ZHANG Qiu

  Lab. Radiat. Biol., Grad. Sch. Sci., Kyoto Univ.

• TACHIBANA Akira

  Radiat. Biol. Cent., Kyoto Univ.

• TAKATORI Kazuhiro

  Lab. Radiat. Biol., Grad. Sch. Sci., Kyoto Univ.

• YONEI Shuji

  Lab. Radiat. Biol., Grad. Sch. Sci., Kyoto Univ.

• Zhang Qiu-mei

  Department Of Biological Sciences Graduate School Of Science Kyoto University

• Zhang Qiu-mei

  Lab. Radiat. Biol. Grad. Sch. Sci. Kyoto Univ.

• Chang Po

  Lab. Radiat. Biol. Grad. Sch. Sci. Kyoto Univ.

• Takatori Kazuhiro

  Lab. Radiat. Biol. Grad. Sch. Sci. Kyoto Univ.

• ZHANG Qiu

  Labo. Radiat. Biol. Grad. Sch. Sci. Kyoto Univ.

• Tachibana Akira

  Radiat. Biol. Cent. Kyoto Univ.

• Yonei S

  Department Of Biological Sciences Graduate School Of Science Kyoto University

• Yonei Shuji

  Lab. Of Radiat. Biol. Graduate School Of Sci. Kyoto Univ.

• Zhang Qiu

  Lab. Radiat. Biol. Grad. Sch. Sci. Kyoto Univ.

• Qiu-mei Zhang

  Kyoto Univ. Fac. Of Sci.

• Yonei Shuji

  Lab. Radiat. Biol. Grad. Sch. Sci. Kyoto Univ.

• Yonei Shuji

  Kyoto Univ. Fac. Of Sci.

• Yonei Shuji

  Lab. Of Radiat. Biol. Graduate School Of Science.

• YONEI Shuji

  Lab. of Radiat. Biol. , Graduate School of Sci. , Kyoto Univ.

関連論文

• 88 Excessive Base Excision Repair of Clustered DNA Damage by E. coli MutM and human Ogg1 Causes Enhanced Sensitivity to Low LET radiation in E. coli(Repair of radiation damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Role of the Escherichia coli and Human DNA Glycosylases That Remove 5-Formyluracil from DNA in the Prevention of Mutations
• Identification of Repair Enzymes for 5-Formyluracil in DNA : Endonuclease III, Endonuclease VIII and MutM Proteins of Escherichia coli
• The Shizosaccharomyces pombe Homolog (SpMYH) of the Escherichia coli MutY Is Required for Removal of Guanine from 8-Oxoguanine/Guanine Mispairs to Prevent G:C to C:G Transversions
• Identification of 8-oxoguanine-DNA Glycosylase/AP Lyase Activity in Extracts from Schizosaccharomyces pombe
• Disruption of the Schizosaccharomyces pombe homolog of MutY (SpMYH).
• Isolation and Characterization of SpMYH, a MutY Homolog, of Fission Yeast Schizosaccharomyces Pombe
• S-3-2 NHEJ pathway plays an important role in low dose-rate effects (LDRE)(Biological Effects of Low Dose and Low Dose-rate Irradiations, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 9 Modulation of nitric oxide-mediated bystander effects by chronic irradiation with gamma-rays(Low dose and low dose-rate effects, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Modulation of NO-Mediated Bystander Effect by Pre-Gamma-Ray Irradiation with Low-Dose Rate
• DNA Synthesis by Escherichia coli DNA Polymerase IV (DinB) on Templates Containing Oxidized Bases
• Development, Beam Characterization and Chromosomal Effectiveness of X-rays of RBC Characteristic X-ray Generator
• Mutations and sequence variability of FAA gene in Japanese Fanconi anemia
• Signaling and Gene Regulation of Adaptive Response to Low-dose Radiations
• Cellular Response to Low-dose Radiations and Its Signal Transduction
• No Induction of p53 Phosphorylation and Few Focus Formation of Phosphorylated H2AX Suggest Efficient Repair of DNA Damage During Chronic Low-dose-rate Irradiation in Human Cells
• 28 AT cells in GI phase are sensitive to low dose rate radiation(Low dose and low dose-rate effects, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Genetic effect of low dose rate radiation on human cells immortalized by introducing the hTERT gene
• End-joining of double-strand breaks in DNA by nuclear extracts from X-irradiated human cells
• Novel mutations of the FANCG gene causing alternative splicing in Japanese Fanconi anemia
• 131 Effects of the Strong Static Magnetic Field on the Expression of Proto-oncogenes in HL-60 Cells(Effects of electro-magnetic fields, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Exposure to Storng Static Magnetic Field Enhances Production of Superoxide Radicals in E. coli
• dentification of Repair Enzymes Recognizing 7,8-Dihydro-8-oxo-guanine Opposite Guanine or Adenine in Escherichia coil
• Cloning and Characterization of Caenorhabditis elegans Gcnes That Correct Hydrogen Peroxide Sensitivity of E. coli oxyR Mutant
• Spectra of Methylene Blue Plus Light-induced Base Substitutions in the supF Gene of Escherichia coli
• Isolation and Characterization of a Novel Mutator Strain of Esche-richia coli That Generates GC-CG Transversions
• Analysis of Junction Sequences of Double-Strand Breaks in Plasmid DNA by Nuclear Extracts from X-Irradiated Mouse Cells
• Analysis of Mutations at the FANCC and FANCG genes in Japanese Fanconi anemia patients
• A High Prevalence of Functional Inactivation by Methylation Modification of P16^/CDKN2/MTS1 Gene in Primary Urothelial Cancers
• Regulation of the Expression of Thioredoxin (trxA) and Thioredoxin Reductase (trxB) Genes in Escherichia coli
• 208 DNA repair function and structural modeling of a putative DNA glycosylase NEIL3(Physics, chemistry and DNA damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Identification of a DNA Glycosylase Activity of Human hNTH1 Protein Acting on 5-Formyluracil, a Major Oxidative Lesion of Thymine
• Identification of a Novel 8-0xoguanine-DNA Glycosylase Activity of Escherichia coli Endonuclease III to Prevent Spontaneous G:C-C:G Transversions
• Effects of Thioredoxin and Glutaredoxin Systems on Regulation of Superoxide Stress Responses in Escherchia coli
• The Effect of 5-Formyluracil, a Major Oxidative Lesion of Thymine, on Biological Function of DNA in vivo and in vitro
• Purification and Characterization of C-C Mismatch-Binding Proteins in Escherichia coli
• Identification of 7,8-Dihydro-8-oxoguanine-DNA Glycosylase Activity of Caenorhabditis elegans
• Regulation of Oxidative Stress Responses by Redox Enzymes in Escherichia coli
• 3'-Blocking Damage of DNA as a Mutagenic Lesion Caused by Hydrogen Peroxide in Escherichia coli
• The Effect of 5-Formyluracil and 5-Hydroxymethyluracil, a Major Oxidative Lesion of Thymine, on Biological Functions of DNA
• Purification and Characterization of C-C Mismatch-binding Proteins in Escherichia coli
• The Escherichia coli HU Protein Regulates DNA Repair through RecA-Dependent and Independent Pathways
• Redox Regulation of Oxidative Stress Responses in Escherichia coli
• Identification and Purification of C-C Mismatch-Binding Protein in Extracts of Escherichia coli
• Roles of the SoxRS Regulon in Spontaneous and Menadione-Induced Reversion to Lac+ in Escherichia coli
• Redox Regulation of Hydrogen Peroxide Stress Response in Escherichia coli
• Induction of Repair Capacity for Oxidatively Damaged DNA as a Component of Peroxide Stress Response in Escherichia coli
• Identification of DNA Damage Causing GC-CG Transversion by Radiation and Its Protective Systems in Escherichia Coli
• Identification of G-G and C-C Mismatch-Binding Activities in Extrads of Schizosaccharomyces Pombe and Escherichia Coli
• Isolation and Characterization of Escherichia coli Mutant That Shows High Frequency of Spontaneous GC-CG transversion
• 4-NQO-Induced Mutations in the lacZ Gene and Repair Pathways in Stationary Phase of Eschericida coli
• Generation, Biological Consequences and Repair Mechanisms of Cytosine Deamination in DNA
• Purification and Characterization of 5-Formyluracil DNA Glycosylase from Human Cells in Culture
• Recombinant Schizosaccharomyces pombe Nth1 Protein Exhibits DNA Glycosylase Activities for 8-oxo-7,8-dihydroguanine and Thymine Residues Oxidized in the Methyl Group
• Identification of Eukaryotic Homologues of Escherichia coil MutY Protein
• Multiple Pathways of Repair for 7,8-Dihydro-8-oxoguanine:C, A, G Mispairs in Escherichia coli
• Analysis of Reapir Pathways for C-C Mismatch in DNA in Escherichia coil
• 218 Overexpression of hOGG1 protein enhanced the sensitivity to killing by gamma-rays in HeLa cells(Physics, chemistry and DNA damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 102 Purification and Characterization of Schizosaccharomyces pombe Nth Homologue(Repair of radiation damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 101 Identification of Caenorabditis elegans Repair Enzymes for Oxidative Base Damage in DNA(Repair of radiation damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 92 Phenotypic Assay of C. elegans Deficient in Uracil DNA Glycosylase Activity(Repair of radiation damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Effects of Redox Enymes on Regulation of Oxidative Stress Responses in Fscherchia coil
• 5-Formyluracil, a Major Product of Thymine Oxidation, Induces Base Substitutions and Deletions on a Plasmid Replicated in Escherichia coli
• Identification of Human Nei Protein as a 5-Formyluracil DNA Glycosylase/AP lyase
• Purification and Characterization of Schizosaccharomyces pombe Nth Homologue
• Phenotypic Properties of C. elegans Defective in Uracil-DNA Glycosylase Activity
• DNA Glycosylases in Base Excision Repair Systems : Specificity and Roles in Prevention of Mutations
• Identification of Binding Activities to 8-Oxoguanine-Containing Oligonucleotides in Extracts Prepared fromSaccharomyces cerevisiae
• Cloning and Characterization of Uracil-DNA Glycosylase Gene of Caenorhabditis elegans
• Identification of 5-Hydroxymethyluracil-DNA Glycosylase Activities in Extracts from Escherichia coli
• Role of WRN exonuclease in repair of DNA double strand breaks
• Characterization of X-ray-induced Mutation in Werner Syndrome Cells
• Spectrum of Spontaneous Mutations in the Cyclic AMP Receptor Protein Gene on Chromosomal DNA of Escherichia coli
• Enzymatic Repair Mechanisms for Base Modifications Induced by Oxygen Radicals
• Experimental Analysis on the Involvement of ATM Gene in the Enhanced Radiosensitivity in AT Cells
• Low transposition frequency of the medaka fish Tol2 element may be due to extranuclear localization of its transposase
• The medaka fish Tol2 transposable element can undergo excision in human and mouse cells
• Development of Alpha-ray Irradiation System.
• Molecular Mechanisms for Transcriptional Regulation of Escherichia coli Endonuclease VIII gene (nei)
• Sensitivity of Escherichia coli Lacking HU Protein to UV Irradiation and a Possible Role of HU Protein in DNA Repair
• Identification of Caenorhabditis elegans Genes That Complement Hydrogen Peroxide Sensitivity of oxyR Mutant of Escherichia coli
• dentification of 5-Formyluracil DNA Glycosylase/AP Lyase Activity of S. cerevisiae Ntg1 and Ntg2 Proteins
• Replication of DNA Templates Containing the 5-Formyluracil, a Major Oxidative Lesion of Thymine in DNA
• The Increase of γ-Ray Sensitivity in E. coli by Overexpression of DNA Glycosylases : Correlationwith the Formation of Clustered Base Damages
• Regulation and Fuctions of Three Soi Genes (Soi-7, Soi-9 and Soi-1O) in Redox Stress Response in Escherichia coli
• The Involvement of Redox Enzymes in Oxidative Stress Response in Escherichia coli
• Molecular analysis of γ-ray-induced mutations at the heterozygous adenine phosphoribosyltransferase locus in human cells.
• Identification of Adenine-DNA Glycosylase Activity in Extracts Prepared from Saccharomyces cerevisiae
• 12 Spectrum of mutations at the mouse Hprt locus induced by ionizing radiation in cells of radioadaptive response(Low dose and low dose-rate effects, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• S-3-3 Reduction of radiation-induced apoptosis by pre-irradiation at a low dose or a low dose-rate(Biological Effects of Low Dose and Low Dose-rate Irradiations, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Depression of Pre-irradiation with a Low Dose-rate on Radiation-induced Mutation
• Molecular Characterization of γ-Ray-Induced 6-Thioguanine-Resistant Mutants of Ataxia-Telangiectasia Cells.
• End-joining of double-strand breaks in DNA by nuclear extracts from X-irradiated mouse cells
• Pre-irradiation with a Low-dose-rate Enhanced DNA-PK Activity and Then Depressed Radiation-inducedApoptosis
• In vitro rejoining of double-strand breaks in DNA by nuclear extracts from X-irradiated mouse cells
• High Frequency of Deletions at the Hypoxanthine-guanine Phosphoribosyl-transferase Locus in an Ataxia-telangiectasia Lymphoblastoid Cell Line Irradiated with γ-Rays
• End-joining of double-strand breaks in DNA by nuclear extracts from X-irradiated p53-deficient mouse cells
• NDX-1 protein hydrolyzes 8-oxo-7, 8-dihydrodeoxyguanosine-5'-diphosphate to sanitize oxidized nucleotides and prevent oxidative stress in Caenorhabditis elegans
• Mutations in mammalian cultured cells
• Towards the establishment of an in vitro system for the rejoining of DNA double strand breaks by cell extracts

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