[SHORT REPORTS]Body and Brain Development following Exposure to <60>^Co γ-Irradiation during Pregnancy in Mice

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概要

• 論文の詳細を見る

• We studied the dose-response effects of γ-irradiation on the weight gains of the body and the brain in ICR mice exposed to various doses of <60>^Co γ-irradiation ranging from 0 to 1.5 Gy on day 13 of pregnancy (E13). We found 0.5 Gy γ-irradiation caused a significant reduction in brain weight but not in body weight amoug 6-week-old mice. Higher doses (1.0,1.5 Gy) seriously inhibited body and brain development, resulting in significantly low weights at 6 weeks of age. A significantly lower brain weight among fetuses exposed to 1.5 Gy was foud as early 24 hours after exposure, while significant reductions in the body weight of these same fetuses appeared 3 days after exposure. The effects of radiation on brain and body development were similar for both males and females.

• 名古屋大学の論文

著者

• 井上 稔

  新日本科学

• Hayasaka Shizu

  Department Of Genetics Research Institute Of Environmental Medicine Nagoya University

• Hayasaka Shizu

  Research Institute Of Environmental Medicine Nagoya University

• 井上 稔

  大阪府立大学 農生命科研究

• Hayasaka Shizu

  名古屋大学環境医学研究所

• Inouye M

  Shin Nippon Biomedical Lab. Ltd. Kagoshima Jpn

• Inouye M

  Nagoya Univ. Nagoya Jpn

• Inouye M

  Research Institute For Environmental Medicine University Of Nagoya

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