METABOLIC DETOXICATION OF BIS-(2-HYDROXY-3,5-DICHLOROPHENYL)-SULFOXIDE IN MAN
スポンサーリンク
概要
- 論文の詳細を見る
The metabolic detoxication of bis(2-hydroxy-3, 5-dichlorophenyl)sulfoxide (BTS) in man was investigated. Bis(2-hydroxy-3, 5-dichlorophenyl)sulfide (BT) was identified in β-glucuronidase treated urine following the administration of BTS by thin-layer chromatography, gas chromatography, ultraviolet spectrum and quantitative analysis. No other metabolites were detectable. BT-glucuronide was also identified in urine. It was assumed that BTS was reduced to BT and successively conjugated with glucuronide in man, and excreted as BT-glucuronide in the urine.
- 日本トキシコロジー学会の論文
- 1981-11-25
著者
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Takahashi Masashi
Dep. Of Radiology Shiga Univ. Of Medical Sci.
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SEKIKAWA HITOSHI
Faculty of Pharmaceutical Sciences, Hokkaido University
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Hayashi Nobuyuki
Hokkaido Meical Affaris Bureau Ministry Of Health And Welfare
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Agata Isao
Faculty Of Pharmaceutical Sciences Higashi-nippon-gakuen University
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Agata Isao
Faculty Of Pharmaceutical Sciences Higashi Nippon Gakuen University
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Takada Masahiko
Department Of Physiology School Of Dentistry At Tokyo Nippon Dental University
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YAGI Naomi
Faculty of Pharmaceutical Scicences, Health Sciences University of Hokkaido
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Takada Masahiko
Faculty Of Pharmaceutical Scicences Health Sciences University Of Hokkaido:(present Address)sapporo
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Takada Masahiko
Faculty Of Pharmaceutical Sciences Higashi-nippon-gakuen University
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Sakamoto Mieko
Faculty Of Pharmaceutical Sciences Higashi-nippon-gakuen University
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ITOH MEGUMI
Faculty of Pharmaceutical Sciences, Higashi-Nippon-Gakuen University
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Itoh Megumi
Faculty Of Pharmaceutical Sciences Higashi-nippon-gakuen University
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Yagi Naomi
Faculty Of Pharmaceutical Scicences Health Sciences University Of Hokkaido
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CHIBA Kazumoto
Faculty of Pharmaceutical Sciences, Higashi-Nippon-Gakuen University
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HIGA Tamotsu
Faculty of Pharmaceutical Sciences, Higashi-Nippon-Gakuen University
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KIYOTA Masato
Faculty of Pharmaceutical Sciences, Higashi-Nippon-Gakuen University
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Sekikawa Hitoshi
Faculty Of Pharmaceutical Scicences Health Sciences University Of Hokkaido
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Yagi Naomi
Faculty Of Pharmaceutical Sciences Health Sciences University Of Hokkaido
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Higa Tamotsu
Faculty Of Pharmaceutical Sciences Higashi-nippon-gakuen University
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Kiyota Masato
Faculty Of Pharmaceutical Sciences Higashi-nippon-gakuen University
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Chiba Kazumoto
Faculty Of Pharmaceutical Sciences Higashi-nippon-gakuen University
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Yagi Naomi
Faculty Of Pharmaceutical Sciences Higashi-nippon-gakuen University
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Takahashi Masashi
Department Of Radiology Shiga University Of Medical Science
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