Controlled release of anticanecr agents through hydrophilic ethylene-vinyl alcohol copolymer membranes.
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概要
- 論文の詳細を見る
Ethylene-vinyl alcohol (EVA1) copolymer was evaluated as a controlling membrane for the release of anticancer agents, 5-fluorouracil and ftorafur. The effect of comonomer ratio modifications on the drug permeation was studied. EVA1 copolymer membranes of ethylene contents of 32, 44, and 47 mol% were used. An increase in ethylene content of EVA1 copolymer decreased the drug permeability through the copolymer membranes.
- 日本膜学会の論文
著者
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MIYAZAKI Shozo
Faculty of Pharmaceutical Sciences, Health Science University of Hokkaido
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Takada Masahiko
Faculty Of Pharmaceutical Scicences Health Sciences University Of Hokkaido:(present Address)sapporo
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Sakamoto Mieko
Faculty Of Pharmaceutical Sciences Higashi-nippon-gakuen University
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Takada Masahiko
Faculty of Pharmaceutical Sciences, Higashi-Nippon-Gakuen University
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Takeuchi Shigemi
Faculty of Pharmaceutical Sciences, Higashi-Nippon-Gakuen University
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- Controlled release of anticanecr agents through hydrophilic ethylene-vinyl alcohol copolymer membranes.