2 Exopolysaccharideを産生する黒色色素産生グラム陰性桿菌について : その同定, 病原性およびexopolysaccharideの化学組成(第498回大阪歯科学会例会)

概要

論文の詳細を見る
We examined the biofilm forming capacity of 74 clinical isolates of black-pigmented Gram-negative anaerobic rods isolated from periodontal lesions. Two strains (OD 1-2 and OD 1-16) were obtained and identified as Prevotell intermedia (P. intermedia). Exopolysaccharide (EPS) from strain OD 1-16 cultures consisted primarily of polysaccharide that was 62% mannose. Compared to the non-EPS-producing strain, ATCC 25611, strain OD 1-16 had a higher capacity to induce abscess formation in mice. Our results suggest that P. intermedia can produce large amounts of exopolysaccharide, form biofilm, and play an important role in the development of biofilm infections in the oral cavity.
大阪歯科学会の論文
2005-06-25