3 難治性根尖性歯周炎から分離されたバイオフィルム様構造をもつ好気性有芽胞グラム陽性桿菌の同定と性状(第498回大阪歯科学会例会)

概要

論文の詳細を見る
We isolated a spore-forming Gram-positive aerobic rod from a persistent periapical lesion that was identified as Bacillus subtilis using an API system, 16 S rRNA sequencing, and DNA-DNA hybridization. We named it B. subtilis strain N 38. Scanning electron microscopy revealed that this strain had dense mesh-like structures on the cell surface, which is typical of biofilm-forming bacteria. Several genes, previously reported as crucial factors for biofilm formation in B. subtilis, were detected by the polymerase chain reaction method. Compared with the ATCC 6051, which is a type strain of B. subtilis, the susceptibility of strain N 38 to anti-microbial agents did not show a particular pattern. Our data suggest that biofilm-forming B. subtilis can cause persistent periapical periodontitis.
大阪歯科学会の論文
2005-06-25