Luteolin Increases the Expression of GRP94 in HeLa Cells
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概要
- 論文の詳細を見る
We found increased expression of GRP94, the 94-kDa glucose-regulated protein, in HeLa cells 24 h after treatment with luteolin. Luteolin increased the levels of GRP94 mRNA and protein, but it did not increase the expression of unfolded protein response (UPR)-regulated genes. In addition, luteolin also enhanced GRP94 promoter activity, suggesting that it enhances the expression of GRP94 at the transcriptional level, not via the UPR signaling pathway.
- 社団法人 日本農芸化学会の論文
- 2009-10-23
著者
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SUZUKI Nobuo
Department of Surgery, Tsuruoka City General Hospital
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Suzuki Toshikazu
Department Of Environmental Biochemistry Graduate School Of Medicine Chiba University
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Shi Qin-wen
Department Of Forensic Medicine Hebei Medical University
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Dong Mei
Department Of Forensic Medicine Hebei Medical University
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HU Gaofeng
Department of Environmental Biochemistry, Graduate School of Medicine, Chiba University
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CONG Bing
Department of Forensic Medicine, Hebei Medical University
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Suzuki Toshikazu
Department Of Biuchemistry And Cell Biology.nalional Institute Of Infectious Diseaser
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Hu Gaofeng
Department Of Environmental Biochemistry Graduate School Of Medicine Chiba University
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Suzuki Nobuo
Department Of Applied Physics Tohoku University
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Cong Bing
Department Of Forensic Medicine Hebei Medical University
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Suzuki Nobuo
Department Of Applied Physics Faculty Of Engineering Tohoku University
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Dong Mei
Department of Clinical Laboratory, 309th Hospital of Chinese People's Liberation Army
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