Effects of Spirulina, a Blue-Green Alga, on Bone Metabolism in Ovariectomized Rats and Hindlimb-Unloaded Mice
スポンサーリンク
概要
- 論文の詳細を見る
The safety and effectiveness were examined of the spirulina alga on bone metabolism in ovariectomized estrogen-deficient rats and hindlimb-unloaded mice. The dosage range was from an amount equal to that recommended in so-called health foods for humans (0.08 g/kg BW/day) to a 100-fold higher dose. The bone mineral density (BMD) of the whole femur and tibia of ovariectomized rats in the any spirulina-treated groups was not significantly different from that of the ovariectomized group, although BMD of the distal femur and proximal tibia was significantly lower in the spirulina-treated groups than in the ovariectomized group after a 6 week-experimental period. BMD of the femur and tibia was not affected by treatment with any dose of spirulina in hindlimb-unloaded mice. These results suggest that the intake of spirulina decreased BMD in the trabecular bone of rodents under estrogen-deficient conditions.
- 社団法人 日本農芸化学会の論文
- 2006-02-23
著者
-
Wu Jian
Division Of Applied Food Research National Institute Of Health And Nutrition
-
ISHIMI YOSHIKO
Division of Food Science, National Institute of Health and Nutrition
-
Ishimi Yoshiko
Division Of Applied Food Research National Institute Of Health And Nutrition
-
Ishimi Yoshiko
国立健康･栄養研究所 食品機能研究部
-
FUJIOKA MAIKO
Division of Applied Food Research, National Institute of Health and Nutrition
-
SUGIYAMA Fumie
Division of Applied Food Research, National Institute of Health and Nutrition
-
EZAKI Junko
Division of Applied Food Research, National Institute of Health and Nutrition
-
Sugiyama Fumie
Division Of Applied Food Research National Institute Of Health And Nutrition
-
Ezaki Junko
Division Of Applied Food Research National Institute Of Health And Nutrition
-
Fujioka Maiko
Division Of Applied Food Research National Institute Of Health And Nutrition
-
Ishimi Yoshiko
Nutritional Epidemiology Program National Inst. Of Health And Nutrition
関連論文
- Androgen Deficiency-induced Bone Loss Can Be Prevented by the Combined Intervention of Exercise and Genistein Administration in Mice.
- Hesperidin, a citrus flavonoid, inhibits bone loss and decreases serum and hepatic lipids in ovariectomized mice.
- Puerariase radix prevents bone loss in ovariectomized mice.
- Puerariae radix prevents bone loss in ovariectomized mice
- Assessment of effectiveness of oral administration of collagen peptide on bone metabolism in growing and mature rats
- Effect of Low Dose Vitamin K2 (MK-4) Supplementation on Bio-Indices in Postmenopausal Japanese Women
- Soybean isoflavones preserve bone mass in hindlimb-unloaded mice
- Effects of Spirulina, a Blue-Green Alga, on Bone Metabolism in Ovariectomized Rats and Hindlimb-Unloaded Mice
- Possible Adverse Effects of Soy Isoflavone Mixture on Pregnant and Lactating Rats and their Suckling Pups
- Effects of Genistein, an Isoflavone, on Pregnancy Outcome and Organ Weights of Pregnant and Lactating Rats and Development of Their Suckling Pups
- Effect of high impact sports on bone health in postmenopausal women
- Combined Intervention of Medium-Chain Triacylglycerol Diet and Exercise Reduces Body Fat Mass and Enhances Energy Expenditure in Rats
- Randomly Interesterified Triacylglycerol Containing Medium- and Long-Chain Fatty Acids Stimulates Fatty Acid Metabolism in White Adipose Tissue of Rats
- Ovariectomy in Mice Decreases Lipid Metabolism-Related Gene Expression in Adipose Tissue and Skeletal Muscle with Increased Body Fat
- Hypoglycemic and Hypolipidemic Effects of Hesperidin and Cyclodextrin-Clathrated Hesperetin in Goto-Kakizaki Rats with Type 2 Diabetes