Paraneoplastic Cerebellar Degeneration (PCD) Associated with Squamous Cell Carcinoma of the Lung
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概要
- 論文の詳細を見る
We report a case of a 71-year-old man who presented with cerebellar dysfunction. He was diagnosed as having squamous cell carcinoma of the lung (T2N3M0, Stage IIIB). No anti-onconeural antibodies were found in his serum. Cerebral spinal fluid (CSF) examination showed mild mononuclear pleocytosis alone. Magnetic resonance imaging (MRI) of the brain and spinal cord revealed no abnormalities. At autopsy, there was complete disappearance of Purkinje cells with reactive astrocytosis. These findings are compatible with paraneoplastic cerebellar degeneration (PCD). To our knowledge, no case of PCD has been reported previously in patients with squamous cell carcinoma of the lung.
- 社団法人 日本内科学会の論文
- 2004-07-01
著者
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Nishimura M
First Department Of Medicine Hokkaido University School Of Medicine
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Nishimura Masaharu
First Department Of Medicine Hokkaido University School Of Medicine
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YAMAZAKI Koichi
First Department of Medicine, Hokkaido University, School of Medicine
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Nakashima M
Department Of Molecular Immunology And Clinical Immunology Medical Institute Of Bioregulation Kyushu
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NAGASHIMA Kazuo
Laboratory of Molecular and Cellular Pathology, Hokkaido University School of Medicine
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Dosaka (akita)
Department Of Medical Oncology Hokkaido University Graduate School Of Medicine
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SAKAI Koichiro
Department of Neurology, Kanazawa Medical College
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KONISHI Jun
First Department of Medicine, Hokkaido University School of Medicine
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Konishi Jun
First Department Of Medicine Hokkaido University School Of Medicine
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CHIKAI Kanako
Laboratory of Molecular & Cellular Pathology, Hokkaido University Graduate School of Medicine
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KINOSHITA Ichiro
Department of Medical Oncology, Hokkaido University Graduate School of Medicine
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Nakashima M
Kyushu Univ. Fukuoka Jpn
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Yamazaki Koichi
First Department Of Medicine Hokkaido University School Of Medicine
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Nagashima Kazuo
Laboratory Of Molecular & Cellular Pathology Hokkaido University School Of Medicine
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Chikai Kanako
Laboratory Of Molecular & Cellular Pathology Hokkaido University Graduate School Of Medicine
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Sakai Koichiro
Department Of Neurology Kanazawa Medical College
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Nishimura Masaharu
First Department Of Medicine Hokkaido University Graduate School Of Medicine
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Nagashima Kazuo
Laboratory Of Molecular & Cellular Pathology Hokkaido University Graduate School Of Medicine
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