Effects of Concanavalin A on Cytokine mRNA Expression in Mouse Liver
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概要
- 論文の詳細を見る
The effects of concanavalin A (Con A) on liver cytokine gene expression was studied in mice. The CD4 mRNA expression in normal liver suggests the presence of CD4<SUP>+</SUP> T cells. The administration of Con A induced interleukin (IL) 1β, IL-2 and IL-2 receptor mRNAs, which implies lymphocyte activation in the liver. Interferon-γ and tumor necrosis factor-α mRNA expressions were increased gradually. The present results showed that Con A induced liver cytokine genes. This cytokine gene induction might have been the result of lymphocyte activation in the liver.
- 社団法人 日本薬理学会の論文
- 1997-10-01
著者
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Kobayashi Tadashi
Research Institute of Angiocardiology and Cardiovascular Clinic, Kyushu University
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Okamoto Toshihiro
Research Laboratories Nippon Chemiphar Co. Ltd.
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Kobayashi T
Tokai Univ. Isehara Jpn
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Kobayashi Tadashi
Research Institute Of Angiocardiology And Cardiovascular Clinic Kyushu University
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Okamoto Toshihiro
Research Laboratories Nippon Chemiphar Co. Ltd
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