A novel murine anti-human Fas mAb which mitigates lymphadenopathy without hepatotoxicity
スポンサーリンク
概要
著者
-
WATANABE Mayumi
Medicinal Safety Research Laboratories, Sankyo, Co., Ltd.
-
Tani Yoshiro
Medical Safety Research Laboratories Sankyo Co. Ltd
-
SERIZAWA Nobufusa
Biomedical Research Laboratories, Sankyo Co. Ltd.
-
Yonehara Shin
Institute for Virus Research, Kyoto University
-
NISHIOKA Kusuki
Institute of Medical Science, St. Marianna University School of Medicine
-
YAMAGUCHI Junko
Biomedical Research Laboratories, Sankyo Co., Ltd.
-
YOSHIDA-KATO Hiroko
Biomedical Research Laboratories, Sankyo Co., Ltd.
-
ICHIKAWA Kimihisa
Biomedical Research Laboratories, Sankyo Co., Ltd.
-
OHSUMI Jun
Biomedical Research Laboratories, Sankyo Co., Ltd.
-
OHTSUKI Masahiko
Neuroscience and Immunology Research Laboratories Sankyo Co., Ltd
-
TAKAHASHI Shu
Biomedical Research Laboratories Sankyo Co., Ltd
-
SHIRAISHI Akio
Neuroscience and Immunology Research Laboratories Sankyo Co., Ltd
-
Yamaguchi J
Sankyo Co. Ltd. Tokyo Jpn
-
Watanabe Mayumi
Medicinal Safety Research Laboratories Sankyo Co. Ltd.
-
Nishioka Kusuki
Institute Of Medical Science St. Marianna University School Of Medicine
-
Nishioka Kusuki
Institute Of Medical Science St. Marianna University
-
Ohsumi Jun
Biomedical Research Laboratories Sankyo Co. Ltd.
-
Yoshida-kato Hiroko
Biomedical Research Laboratories Sankyo Co. Ltd.
-
Takahashi Shu
Biomedical Research Laboratories Sankyo Co. Ltd
-
Yonehara S
Graduate School Of Biostudies And Institute For Virus Research Kyoto University
-
Yonehara Shin
Institute For Virus Research Kyoto University
-
Shiraishi Akio
Neuroscience And Immunology Research Laboratories Sankyo Co. Ltd
-
Yamaguchi Junko
Biomedical Research Laboratories Sankyo Co. Ltd.
-
Ichikawa Kimihisa
Department Of Applied Microbiology Nippon Roche Research Center
-
Ohtsuki M
Neuroscience And Immunology Research Laboratories Sankyo Co. Ltd
-
Ohtsuki Masahiko
Neuroscience And Immunology Research Laboratories
-
Ichikawa Kimihisa
Biomedical Research Laboratories Sankyo Co. Ltd.
-
Serizawa N
Biomedical Research Laboratories Sankyo Co. Ltd.
-
Serizawa Nobufusa
Biomedical Research Laboratories Sankyo Co. Ltd.
-
Watanabe Mayumi
Medical Safety Research Laboratories Sankyo Co. Ltd
-
NISHIOKA Kusuki
Institute of Innovative Medical Science and Education, Tokyo Medical University
関連論文
- A NOVEL MODEL OF CONTINUOUS DEPLETION OF GLUTATHIONE IN MICE TREATED WITH L-BUTHIONINE (S,R)-SULFOXIMINE
- 21C-04-2 Correlation between Localization of CYP1A1/2 and Aryl Hydrocarbon Receptor in the Liver Lobule of Rats Treated with 3-methylcholantherene(3MC) or β-Naphthoflavone (BNF).
- Effects of Growth Hormone on Bone in Mini Rats
- Comparison of Bone Changes between Neonatally Monosodium Glutamate-Treated Rats and Mini Rats
- Effects of phenobarbital, a drug-metabolizing enzymes inducer, on hepatic DNA ploidy in hepatectomized rats
- Effects of Exogenous Growth Hormone (GH)-Treatment on Carbon Tetrachloride (CCl_4)-Induced Acute Liver Injury in GH-Deficient Mini Rats
- RESTITUTIVE RESPONSE OF MINI RAT LIVER TO INJURY INDUCED BY A SINGLE ORAL ADMINISTRATION OF THIOACETAMIDE
- Expression of CYP3A4 mRNA Is Correlated With CYP3A4 Protein Level and Metabolic Activity in Human Liver
- Effects of Ovariectomy and Estrogen Replacement on Aota Angiotensin-Converting Enzyme Activity in Rats
- Direct Formation of Human Interleukin-11 by Cis-Acting System of Plant Virus Protease in Escherichia coli
- Oxidized low-density lipoprotein (OxLDL) upregulates the expression of SR-PSOXICXCL16, a novel OxLDL receptor as well as a transmembrane CXC chemokine
- Effect of feeding condition on gene expression analysis using DNA chip.(GENERAL SESSION BY POSTER PRESENTATION)(MOLECULAR TOXICITY & TOXICOGENOMICS)
- Proteomic Surveillance of Autoantigens in Relapsing Polychondritis
- Humanization of the Mouse Anti-Fas Antibody HFE7A and Crystal Structure of the Humanized HFE7A Fab Fragment
- Crystal Structure of the Antigen-Binding Fragment of Apoptosis-Inducing Mouse Anti-Human Fas Monoclonal Antibody HFE7A
- Implications of transcriptional coactivator CREB binding protein complexes in rheumatoid arthritis
- A novel murine anti-human Fas mAb which mitigates lymphadenopathy without hepatotoxicity
- Utilization of Human Liver Microsomes to Explain Individual Differences in Paclitaxel Metabolism by CYP2C8 and CYP3A4
- Osteosarcomas in the Lungs of an ICR Mouse
- High-performance liquid chromatographic method for determination of DDT and its degradation products in rat plasma, liver and brain : validation and application to a pharmacokinetic study
- The analytical method for determination of DDT and its metabolite in rat plasma, liver and brain, and their concentrations after single oral administration.
- A FURTHER STUDY ON THE RELIABILITY OF TOXICOKINETIC PARAMETERS FOR PREDICTING HEPATOTOXICITY IN RATS RECEIVING A 28-DAY REPEATED ADMINISTRATION OF DDT
- A COMPARATIVE STUDY ON THE RELIABLILITY OF TOXICOKINETIC PARAMETERS FOR PREDICTING HEPATOTOXICITY OF DDT IN RATS RECEIVING A SINGLE OR REPEATED ADMINISTRATION
- Structures of Thermoactinomyces vulgaris R-47 α-Amylase II Complexed with Substrate Analogues
- Analysis of Catalytic Residues of Thermoactinomyces vulgaris R-47 α-Amylase II (TVA II) by Site-directed Mutagenesis
- Immunohistochemical observation of Fas in the human liver: light and electron microscopic obseervation by immuno-peroxidase method
- Purification, Characterization, and Subsite Affinities of Thermoactinomyces vulgaris R-47 Maltooligosaccharide-metabolizing Enzyme Homologous to Glucoamylases
- Purification and Characterization of Pyridoxine 5'-Phosphate Phosphatase from Sinorhizobium meliloti
- Biosynthesis of Vitamin B_6 in Rhizobium : In Vitro Synthesis of Pyridoxine from 1-Deoxy-D-xylulose and 4-Hydroxy-L-threonine(Biochemistry & Molecular Biology)
- Production of Vitamin B_6 in Rhizobium
- Functional significance of the Fas molecule in naive lymphocytes
- Cloning and Expression of a Novel Murine Anti-human Fas Antibody
- Reducing-agents-mediated Solubilization and Activation of Debranching Enzyme (Pullulanase) in Rice Flour
- 404 SUBMAXILLARIECTOMY ENHANCED THE INHIBITORY ACTION OF ANDROGEN PRODUCTION IN TESTIS BY KETOCONAZOLE
- 403 INDOMETHACIN INDUCED REDUCTION OF OVARIAN FUNCTION TO HYPOGONADISM
- Prediction of Plasma concentration profiles in feeding study from the data on single oral administration : Application to toxicokinetic study of DDT in F344 male rats.
- Induction of Fas-dependent apoptosis in synovial infiltrating cells in rheumatoid arthritis
- Inverse wrap : an improved implantation technique for virus-transduced synovial fibroblasts in the SCID mouse for rheumatoid arthritis
- Effects of Glucosamine/Chondroitin Supplement on Osteoarthritis : Involvement of PGE_2 and YKL-40
- Amelioration of systemic autoimmune disease by the stimulation of apoptosispropoting recptor Fas with anti-Fas mAd
- Phosphorylation of Fas-associated Death Domain Contributes to Enhancement of Etoposide-induced Apoptosis in Prostate Cancer Cells
- High-Level Secretory Production of Phospholipase A_1 by Saccharomyces cerevisiae and Aspergillus oryzae
- Molecular Cloning and Expression of the Gene Encoding a Phospholipase A_1 from Aspergillus oryzae
- Importance of the Carboxy-terminus of Human Interleukin-11 in Conserving Its Biological Activity
- NOVEL ADIPOGENESIS INHIBITORY FACTOR (AGIF) : ITS STRUCTURE AND FUNCTION
- ENHANCEMENT OF ADRENAL ANDROGEN-BIOSYNTHESIS BY THE ADMINISTRATION OF AA560 NAMED ANTIANDROGEN
- Potential of Lansoprazole as a Novel Probe for Cytochrome P450 3A Activity by Measuring Lansoprazole Sulfone in Human Liver Microsomes
- Age-related thymic involution is mediated by Fas on thymic epithelial cells
- Reduction of Thymocyte Numbers in Transgenic Mice Expressing Viral FLICE-Inhibitory Protein in a Fas-Independent Manner
- Concise paper: Colestimide, an ion-exchange resin agent, may enhance glucose lowering effect of voglibose as their acute effect
- Polymorphism of warfarin related genes (VKORC1 and CYP2C9) analyzed by the smart amplification process method in patients with atrial fibrillation
- Production of Functional Human Selenocysteine-Containing KDRF/Thioredoxin Reductase in E. coli
- Two morphological groups derived from Clonostachys cylindrospora and their relationship to trans-4-hydroxy-(L)-proline productivity
- Fermentative Production of trans-4-Hydroxy-L-proline by Clonostachys cylindrospora
- Cerivastatin induces type-I fiber-, not type-II fiber-, predominant muscular toxicity in the young male F344 rats
- Severe impairment of B cell function in lpr/lpr mice expressing transgenic Fas selectively on B cells
- IL-4 and anti-CD40 prtect against Fas-mediated B cell apoptosis and induce B cell growth and differentiation
- Reblastatin, a Novel Benzenoid Ansamycin-type Cell Cycle Inhibitor
- Combination of two-dimensional electrophoresis and shotgun peptide sequencing in comparative proteomics
- Synthetic Strategy for Long Peptides
- Isolation and Characterization of the Gene Conferring Thiamine-inducible Expression from Saccharomyces cerevisiae
- Extracellular Processing of Carboxypeptidase Y Secreted by a Saccharomyces cerevisiae ssl1 Mutant Strain
- Thiamine Increases Expression of Yeast Gene
- Secretion and Overproduction of Carboxypeptidase Y by a Saccharomyces cerevisiae ssl1 Mutant Strain
- Fas-induced in vivo Apoptosis in Bone Marrow : Anti-Fas mAb-induced Elimination and Successive Proliferation of Fas-expressing Cells Especially Those of Myeloid Lineage
- Fermentative Production of cis-4-Hydroxy-(L)-proline by Helicocerus oryzae and Acrocylindrium oryzae
- Cerivastatin induces type-I fiber-, not type-II fiber-, predominant muscular toxicity in the young male F344 rats
- Comparison of the Effects of Omeprazole and Rabeprazole on Ticlopidine Metabolism In Vitro
- APOPTOSIS AND FAS ANTIGEN
- The Japanese version of the 2010 American College of Rheumatology Preliminary Diagnostic Criteria for Fibromyalgia and the Fibromyalgia Symptom Scale : reliability and validity
- Which subgroup of rheumatoid arthritis patients benefits from switching to tocilizumab versus etanercept after previous infliximab failure? A retrospective study
- Anti-Fas lgG1 antibodies recognizing the same epitope of Fas/APO-1 mediate different biological effects in vitro
- Hepatic CYP1A Induction in 3-Methylcholanthrene-Treated Transgenic Rats with Insufficient Blood Growth Hormone
- Crystal Structure of the Antigen-Binding Fragment of Apoptosis-Inducing Mouse Anti-Human Fas Monoclonal Antibody HFE7A.
- Production of Functional Human Selenocysteine-Containing KDRF/Thioredoxin Reductase in E, coli.
- The Japanese version of the modified ACR Preliminary Diagnostic Criteria for Fibromyalgia and the Fibromyalgia Symptom Scale : reliability and validity