Fermentative Production of cis-4-Hydroxy-(L)-proline by Helicocerus oryzae and Acrocylindrium oryzae
スポンサーリンク
概要
- 論文の詳細を見る
The production of hydroxyproline by microorganisms was studied to discover the chiral source of the side chain moiety of carbapenem. cis-4-Hydroxy-(L)-proline produced by Helicocerus oryzae and A crocylindrium oryzae was purified from culture broths. The ^1NMR spectra and [α]_D of purified samples were in agreement with those of standard samples. Our finding provided the first evidence for fermentative production of cis-4-hydroxy-(L)-proline. The addition of (L)-proline to the culture broth of H. oryzae increased the production of cis-4-hydroxy-(L)-proline.
- 社団法人日本農芸化学会の論文
- 1994-09-23
著者
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MATSUOKA Tatsuji
Biomedical Research Laboratories, Sankyo Co., Ltd.
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Furuya K
Sankyo Co. Ltd. Tokyo Jpn
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Furuya Kouhei
Tsukuba Research Laboratories Sankyo Co. Ltd.
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Serizawa N
Biomedical Research Laboratories Sankyo Co. Ltd.
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Serizawa Nobufusa
Biomedical Research Laboratories Sankyo Co. Ltd.
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Matsuoka Tatsuji
Biomedical Research Laboratories Sankyo Co. Ltd.
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