Osada Hiroyuki | Antibiotic Laboratory Riken (institute Of Physical And Chemical Research)

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概要

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著作論文

Inhibition of bone and muscle metastases of lung cancer cells by a decrease in the number of monocytes/macrophages
Nordihydroguaiaretic Acid, of a New Family of Microtubule-stabilizing Agents, Shows Effects Differentiated from Paclitaxel(Biochemistry & Molecular Biology)
P-179 ABSOLUTE STEREOCHEMISTRY AND MOLECULAR TARGET OF ANTITUMOR MACROLIDES, IEJIMALIDES
Iejimalides Show Anti-Osteoclast Activity via V-ATPase Inhibition
New Pyrrolobenzodiazepine Antibiotics, RK-1441A and B : I. Biological Properties(Organic Chemistry)
Epiderstatin and Its Related Glutarimide Antibiotics Inhibit the Cell Growth Induced by Mitogen Stimulation(Biological Chemistry)
Synthesis and Biological Activity of Aminoacyl Analogs of Ascamycin(Organic Chemistry)
Nocardamin Production by Streptomyces avermitilis
Azaspirene, a fungal product, inhibits angiogenesis by blocking Raf-1 activation
A New Trichostatin Derivative, Trichostatin RK, from Streptomyces sp. RK98-A74
A Facile and Effective Screening Method p21^ Promoter Activators from Microbial Metabolites
2P-160 t-BuOOH誘導性細胞死におけるCypDの役割 : ミトコンドリアによるATP供給への関与(細胞生物的課題(接着,運動,骨格,伝達,膜),第47回日本生物物理学会年会)
Specific regulation of cytokine-dependent p38 MAP kinase activation by p62/SQSTM1
Fascinating Bioactive Compounds from Actinomycetes
Synthesis of Pironetin and Related Analogs : Studies on Structure-Activity Relationships as Tubulin Assembly Inhibitors
P-480 PHOTO-CROSS-LINKED SMALL-MOLECULE AFFINITY MATRIX FOR FACILITATING CHEMICAL GENETICS
Biotransformation of the Mycotoxin, Zearalenone, to a Non-estrogenic Compound by a Fungal Strain of Clonostachys sp.(Organic Chemistry)
RK-95113, a New Angiogenesis Inhibitor Produced by Aspergillus fumigatus
Factumycin and Its New Derivative RK-1009 Enhance Threonine-phosphorylation of a 60-kDa Protein in Streptomyces griseus
Inhibition of Telomerase Activity by Fungus Metabolites, CRM646-A and Thielavin B
P-538 TOTAL SYNTHESIS OF PANEPOPHENANTHRIN AND BIOLOGICAL ACTIVITIES OF ITS DERIVATIVES
P-65 BIOMIMETIC OXIDATIVE DIMERIZATION FORMING EPOXYTWINOL A AND ITS COMPUTATIONAL ANALYSIS
RKTS-33, an Epoxycyclohexenone Derivative That Specifically Inhibits Fas Ligand-Dependent Apoptosis in CTL-Mediated Cytotoxicity
Protein Phosphatase 2A Inhibitors, Phoslactomycins. Effects on the Cytoskeleton in NIH/3T3 Cells
Reveromycin A Inhibits Antigen Receptor-mediated Antigen Presentation by B Lymphoma Cells via Its Effect on Intracellular Trafficking of the Antigen
Identification of Saccharomyces cerevisiae Ribosomal Protein L3 as a Target of Curvularol, a G_1-Specific Inhibitor of Mammalian Cells
Dephosphorylation of Bcl-2 by protein phosphatase 2A results in apoptosis resistance
Heparanase as a molecular target of cancer chemotherapy
Epoxyquinol B, a Fungal Metabolite with a Potent Antiangiogenic Activity
Osteoclast-targeting small molecules for the treatment of neoplastic bone metastases
Epoxyquinol B, a Naturally Occurring Pentaketide Dimer, Inhibits NF-κB Signaling by Crosslinking TAK1
Bcl-2 Inhibits Calcineurin-mediated Fas Ligand Expression in Antitumor Drug-treated Baby Hamster Kidney Cells
Robust and Systematic Drug Screening Method Using Chemical Arrays and the Protein Library : Identification of Novel Inhibitors of Carbonic Anhydrase II
Actinomycetes, How Fascinating Microorganisms
Morphological Changes of Human Myeloid Leukemia K562 Cells by a Protein Phosphatase Inhibitor, Tautomycin
A cell-based screening to detect inhibitors of BRAF signaling pathway
Identification and Characterization of an Inhibitor of Trichothecene 3-O-Acetyltransferase, TRI101, by the Chemical Array Approach
Exploitation of Heparanase Inhibitors from Microbial Metabolites Using an Efficient Visual Screening System
Fungal metabolite, epoxyquinol B, crosslinks proteins by epoxy-thiol conjugation
Isolation of new polyketide metabolites, linearolides A and B, from Streptomyces sp. RK95-74

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