Paraneoplastic Neurological Syndrome in a Patient with Squamous Cell Lung Cancer

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概要

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• A 78-year-old man presented with urinary retention and difficulty walking. Both legs showed muscle weakness, and he was experiencing lower body hypoesthesia. T2-weighted magnetic resonance imaging revealed lesions with high signal intensity and enhancement in the spinal cord and cerebrum. A cerebrospinal fluid specimen showed inflammatory changes, but negative cytology findings. Chest computed tomography revealed a tumor measuring 40 mm in diameter, and a lung biopsy revealed the presence of squamous cell carcinoma. We diagnosed the patient with paraneoplastic neurological syndrome related to lung cancer. The patient was treated with steroid pulse therapy and chemotherapy, which relieved the symptoms and enabled the patient to achieve an independent gait.

著者

• Yamada Osamu

  Department Of Cardiovascular Dynamics National Cardiovascular Center Research Institute

• Minatoguchi Shinya

  The Second Department Of Internal Medicine Gifu University Graduate School Of Medicine

• Mori Hidenori

  Department Of Animal Science School Of Agriculture Ibaraki University

• Yanase Komei

  The Second Department of Internal Medicine, Gifu University Graduate School of Medicine, Japan

• Ito Fumitaka

  The Second Department of Internal Medicine, Gifu University Graduate School of Medicine, Japan

• Ohno Yasushi

  The Second Department of Internal Medicine, Gifu University Graduate School of Medicine, Japan

• Kaito Daizo

  The Second Department of Internal Medicine, Gifu University Graduate School of Medicine, Japan

• Endo Junki

  The Second Department of Internal Medicine, Gifu University Graduate School of Medicine, Japan

• Morishita Megumi

  The Second Department of Internal Medicine, Gifu University Graduate School of Medicine, Japan

• Funaguchi Norihiko

  The Second Department of Internal Medicine, Gifu University Graduate School of Medicine, Japan

• Mori Hidenori

  Department of Respiratory Medicine, Hashima Community Medical Center, Japan

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