Intravenous Indomethacin Therapy in Infants With a Patent Ductus Arteriosus Complicating Other Congenital Heart Defects
スポンサーリンク
概要
- 論文の詳細を見る
In the present study, 0.2-0.6 mg/kg (0.4±0.2, mean ± standard deviation) indomethacin was administered intravenously to close a patent ductus arteriosus in 13 infants with co-existing congenital heart defects whose ages ranged from 3 to 48 (14±14) days. All of them were hemodynamically ductus-independent and symptomatic. Echocardiography demonstrated that the ductus had closed in 8 infants, aged 3-33 (12±10) days (responders), but had not closed in 5 infants aged 6-48 (19±19) days (non-responders). There was no significant difference between the responders and non-responders in their age, body weight, minimal diameter of the duct, dose of indomethacin, gestational age, birthweight, or Apgar score. One possible major complication might be associated with indomethacin. However, intravenous indomethacin should be considered prior to surgial ligation as one option for infants with a symptomatic patent ductus arteriosus complicated by other congenital heart defects. (CircJ 2003; 67: 750-752)
- 社団法人日本循環器学会の論文
- 2003-08-20
著者
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富田 英
Cardiovascular Center Showa University Northern Yokohama Hospital
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TOMITA Hideshi
Department of Pediatrics, Sapporo Medical University School of Medicine
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TOMITA Hideshi
Japanese Society of Pediatric Interventional Cardiology
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Watanabe Ken
Department of Pediatrics, National Cardiovascular Center
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Kurosaki Ken-ichi
Department of Pediatrics, National Cardiovascular Center
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Echigo Shigeyuki
Department of Pediatrics, National Cardiovascular Center
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Yamada Osamu
Department Of Pediatric Cardiology Division Of Cardiology National Cardiovascular Center
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Ono Yasuo
Department Of Pediatrics National Cardiovascular Center Osaka University Medical School
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Tomita Hideshi
昭和大学横浜市北部病院 循環器センター
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Tomita Hideshi
札幌医科大学 小児科
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Tomita Hideshi
Division Of Cardiology Showa University Northern Yokohama Hospital
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Ono Yasuo
Departments Of Pediatrics National Cardiovascular Center
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Tomita Hideshi
Department Of Materials Chemistry Faculty Of Engineering Yokohama National University
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Kurosaki Ken-ichi
Department Of Pediatric Cardiology Division Of Cardiology National Cardiovascular Center
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Kurosaki Ken-ichi
Department Of Functional Materials Science Faculty Of Engineering Saitama University
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Yamada Osamu
Department Of Cardiovascular Dynamics National Cardiovascular Center Research Institute
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Ono Yasuo
Department Of Cardiology Shizuoka Children's Hospital
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Echigo Shigeyuki
The Japanese Society of Pediatric Cardiology and Cardiac Surgery Joint Working Groups
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Yamada Osamu
Department Of Pediatrics National Cardiovascular Center
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Echigo Shigeyuki
Department Of Pediatrics Nara Medical University
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Echigo Shigeyuki
Department Of Pediatrics National Cardiovascular Center
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Echigo Shigeyuki
Department Of Pediatric Cardiology National Cardiovascular Center
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Echigo Shigeyuki
Department Of Pediatrics Cardiac Surgery National Cardiovascular Center Osaka.
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Tomita Hideshi
Department Of Pediatrics National Cardiovascular Center
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Ono Yasuo
Department Of Pediatrics Sapporo Medical University School Of Medicine
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Ono Yasuo
National Cardiovascular Center. Dept. Of Pediatrics
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Watanabe Ken
Department Of Pediatrics National Cardiovascular Center
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Watanabe Ken
Department Of Civil Engineering Faculty Of Engineering Tokyo Institute Of Technology
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Echigo Shigeyuki
Pediatrics National Cardiovascular Center
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Ono Yasuo
Department Of Bacteriology Teikyo University School Of Medicine
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Kurosaki Ken-ichi
Department Of Pediatrics National Cardiovascular Center
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Watanabe Ken
Department Of Bone And Joint Disease Research Institute National Center For Geriatrics And Gerontology (ncgg)
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