Plasma Thromboxane B_2 Concentration in Patients With Ventricular Septal Defect and Pulmonary Hypertension
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概要
- 論文の詳細を見る
Plasma thromboxane B_2 (TXB_2)-a stable metabolite of thromboxane A_2 (TXA_2)-conventional hemodynamic parameters, mean pulmonary input energy (input energy), and mean pulmonary output energy (output encrgy) were measured to assess platelet activation in 21 patients with pulmonary hypertension and a ventricular septal defect (VSD). The patients were divided into 2 groups: group A (normal range) and group B (high level). TXB_2 levels were measured by radioimmunoassay. There was no relationship between plasma TXB_2 concentrations and conventional hemodynamic parameters except the pulmonary-to-systemic pressure ratio. Output-to-input energy ratio was correlated logarithmically with the plasma TXB_2 concentration. We concluded that patients with output/input energy ratio >0.15 had a high TXB_2 concentration and activated platelets in pulmonary capillaries.
- 社団法人日本循環器学会の論文
- 1998-02-20
著者
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富田 英
Cardiovascular Center Showa University Northern Yokohama Hospital
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FUSE Shigeto
Department of Pediatrics, Sapporo Medical University School of Medicine
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TOMITA Hideshi
Department of Pediatrics, Sapporo Medical University School of Medicine
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Tomita Hideshi
昭和大学横浜市北部病院 循環器センター
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Tomita Hideshi
札幌医科大学 小児科
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Tomita Hideshi
Division Of Cardiology Showa University Northern Yokohama Hospital
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Tomita Hideshi
Department Of Materials Chemistry Faculty Of Engineering Yokohama National University
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CHIBA Shunzo
Department of Pediatrics Sapporo Medical University School of Medicine
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Fuse Shigeto
Department Of Pediatrics Sapporo Medical University Hospital
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Fuse Shigeto
Department Of Pediatrics Sapporo Medical University
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Chiba Shunzo
Department Of Pediatrics Sapporo Medical University
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Chiba Shunzo
Department Of Pediatrics Faculty Of Medicine Sapporo Medical University
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Fuse Shigeto
Department Of Pediatrics Ntt East Sapporo Hospital
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