Evaluation of Food-derived Functional Ingredients According to Activation of PPAR and Suppression of COX-2 Expression
スポンサーリンク
概要
- 論文の詳細を見る
The peroxisome proliferator-activated receptors (PPARs) are ligand-dependent transcription factors belonging to the nuclear receptor family. They are considered molecular targets for the prevention of lifestyle-related diseases and are involved in the control of cyclooxygenase (COX)-2 expression. COX-2, the rate-limiting enzyme in prostaglandin biosynthesis, plays a key role in inflammation and circulatory homeostasis, and its expression is partly controlled by PPAR. We have identified several natural chemicals, such as resveratrol, that activate PPARs and suppress COX-2 expression. In this review, we provide an evaluation of food-derived functional ingredients that target PPARs and COX-2.
著者
-
Inoue Hiroyasu
Department Of Applied Chemistry Faculty Of Technology Kanagawa University
-
Nakata Rieko
Department Of Food Science And Nutrition Nara Women's University
-
INOUE Hiroyasu
Department of Food Science and Nutrition, Nara Women's University
-
TAKAI Ayako
Department of Food Science and Nutrition, Nara Women's University
-
TAKIZAWA Yoshie
Department of Food Science and Nutrition, Nara Women's University
-
TAKIZAWA Yoshie
Department of Food Science and Nutrition, Nara Women's University
関連論文
- 小児期に骨髄移植を受けた患児の甲状腺機能の変化
- The Kinetics of Immune Reconstitution after Cord Blood Transplantation and Selected CD34^+ Stem Cell Transplantation in Children : Comparison with Bone Marrow Transplantation
- The Generation of Immunocompetent Dendritic Cells From CD34^+ Acute Myeloid or Lymphoid Leukemia Cells
- Progressive multifocal leukoencephalopathy after allogeneic bone marrow transplantation for Wiskott-Aldrich syndrome
- Proton-Transferred Ion Pairs of p-Hydroxybenzaldehyde and p-Hydroxyacetophenone in Ethers at Low Temperature
- Refolding and Activation of Human Prorenin Expressed in Escherichia coli : Application of Recombinant Human Renin for Inhibitor Screening
- Association Behavior of 1-Pyrenyl Pendants Introduced into the Papain Active Site
- The Role of α-Chymotrypsin Active Site in the Proton Dissociation of Aromatic Sulfonium-Salt Pendants Attached to the Methionine-192 Residue
- Self-Sensitized Photolysis of N-(1-Naphthoyl)-N-phenyl-O-(benzoyl-substituted benzoyl)hydroxylamines
- Absorption and Phosphorescence Spectra of Xanthone : Dimer and Tetramer Formations at Low Temperatures
- Observation of Domain Structure in Triglycine Sulfate by a Pyroelectric Probe Technique
- Facile Degradation of Apolipoprotein B by Radical Reactions and the Presence of Cleaved Proteins in Serum
- Functional Expression of Miraculin, a Taste-Modifying Protein in Escherichia Coli
- Effects of Chronic Betaine Ingestion on Methionine-Loading Induced Plasma Homocysteine Elevation in Rats
- Citronellol and Geraniol, Components of Rose Oil, Activate Peroxisome Proliferator-Activated Receptor α and γ and Suppress Cyclooxygenase-2 Expression
- Current Problems of food intake in young women in Japan : Their influence on female reproductive function
- Base-Catalyzed Acyl Exchange Reactions of N,O-Diacyl-o-aminophenols. Substituent and Temperature Effects on the Equilibrium Constants
- Determination of Folate Derivatives in Rat Tissues during Folate Deficiency
- Recent Advances in the Study on Resveratrol
- Evaluation of Food-derived Functional Ingredients According to Activation of PPAR and Suppression of COX-2 Expression
- The photochemical reaction of benzo(c)cinnoline. IV. Comments on the mechanism of 2,2'-diaminobiphenyl formation.
- Intersystem Crossing of Radical Pair in Solvent Cage. External Heavy Atom Effect on Dual Photoreactions of Phthalazine.
- Mechanism of the pyrene-sensitized photolysis of N-(1-naphthoyl)-O-(p-toluoyl)-N-phenylhydroxylamine.
- The Polarized Absorption Spectra of Some β-Substituted Anthraquinones
- The Polarized Absorption Spectra of Some α-Aminoanthraquinones
- Electronic Spectra of Biphenyl and Fluorene
- The Dichroic Spectra of Hydroxy Derivatives of Naphthalene, Anthracene, and Phenanthrene in Polyvinylalcohol Sheets
- Photochemical reactions of phthalazine in 2-propanol.
- Tertiary amine-catalyzed acyl group-exchange reactions of N,O-diacyl-o-aminophenols.
- Proton-transferred ion pairs of p-hydroxybenzaldehyde and p-hydroxyacetophenone in ethers at low temperature.
- The photolysis of N,O-diacyl-N-phenylhydroxylamines.
- Benzophenone-Sensitized Photolysis of N,N-Dibenzyl-O-acylhydroxylamines. Mechanism of the Imine-Forming Radical Elimination Reaction.
- Tertiary amine-catalyzed acyl group exchange reaction of N,O-diacyl-o-aminophenols. Its mechanism and factors determining the relative stability of acyl exchanged isomer pairs.
- Spectrophotometric Studies of the Acidities of Dichlorophene and Hexachlorophene
- The Photochemical Reaction of Benzo[c]cinnoline. I. The Photoreduction and Subsequent Reactions in Acidified Alcohols
- The Solvent Effect on the Stability of α-Pyridoin
- Intramolecular Charge-transfer Interaction in Substituted Diphenylmethanes
- Growth and Endocrine Function in Long-term Adult Survivors of Childhood Stem Cell Transplant
- Evaluation of Food-derived Functional Ingredients According to Activation of PPAR and Suppression of COX-2 Expression