Cellular Responses to Electrochemical Killing Process by Applying a Constant Potential in Synchronously Cultured Saccharomyces Cerevisiae
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概要
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To elucidate the mechanism of the electrochemical killing, the global gene expression of synchronously cultured Saccharomyces cerevisiae exposed to electrochemical stimulus was analyzed using DNA microarray. By applying a potential of 1.0 V vs. saturated calomel electrode (SCE), oxidative stress related genes were expressed after only 5 minutes. The gene for cta1 exhibited the highest expression level, while ROS gradually accumulated inside the cells. Genes for signal transduction which may be related to cellular apoptosis were also seen expressed.
著者
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Matsunaga Tadashi
Department Of Applid Chemistry For Resources Tokyo University Of Agriculture And Technology
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Takeyama Haruko
Department Of Biotechnology Tokyo University Of Agriculture And Technology
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Suzuki Takeyuki
Department Of Applied Chemistry Graduate School Of Engineering Tokyo University Of Agriculture And T
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Mori Tetsushi
Department Of Biotechnology Tokyo University Of Agriculture And Technology
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Suzuki Takeyuki
Department of Biotechnology, Tokyo University of Agriculture and Technology
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OKAMURA Yoshiko
Department of Biotechnology, Tokyo University of Agriculture and Technology
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