8歳女児の原発性肺癌の一例

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A case of 8-year-old girl with primary lung cancer is presented in this report. She experienced fever and cough in July 1991. Chest radiographs on admission showed the infiltrations of the right upper lobe and atelectasis of the right middle and the lower lobe. The diagnosis of squamous cell carcinoma was made by transbronchial biopsy with bronchoscopy. She was treated with radiotherapy with vindesine, cisplatin and mitomycin C. Complete response was achieved by this therapy. However, metastasis of the bone and the liver occured. She died 8 monthes after onset. Only 28 cases of primary lung cancer under 15-year-old were reported previously in Japan. The survival time of 15 cases with small cell carcinoma or non-small cell carcinoma in advanced stage was not different from that of adult cases previously reported. 5 children in stage I or II were operated curatively and remain alive with no sign of recurence over 5 years.