Chiral and stereoselective total synthesis of (-)-deoxoprosopinine and (-)-deoxoprosophylline. Intramolecular aminomercuration of an .EPSILON.,.ZETA.-unsaturated amine.
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概要
- 論文の詳細を見る
L-Serine was transformed in 8 steps into (4<I>R</I>,5<I>S</I>)-2,2-dimethyl-4-[(Z)-3-pentadecenyl]-1,3-dioxan-5-amine. This chiral ε,ζ-unsaturated amine was subjected to intramolecular aminomercuration and then acid hydrolysis to give (−)-deoxoprosopinine and (−)-deoxoprosophylline.
- 公益社団法人 日本化学会の論文
著者
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Hirota Hiroshi
Department Of Chemistry Faculty Of Science The University Of Tokyo
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Takahashi Takeyoshi
Department Of Applied Biological Science College Of Agriculture And Veterinary Medicine Nihon Univer
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Moriyama Yoshihiko
Institute of Chemistry, Kyoto Prefectual University of Medicine
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Saitoh Yutaka
Department of Chemistry, Faculty of Science, The University of Tokyo
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Khuong-Huu Qui
Institut de Chimie des Substances Naturelles, Centre National de la Recherche Scientifique
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