The conversion of (+)-dehydroabietic acid into steroidal hormones.
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概要
- 論文の詳細を見る
A resin acid, (+)-dehydroabietic acid, was converted into 3,4,4a,9,10,10a-hexahydro-7-methoxy-10aβ-methyl-4aα<I>H</I>-phenanthren-1(2<I>H</I>)-one (<B>2</B>) by the introduction of oxygen functions at the C-4 and C-13 positions, and a rearrangement of the angular methyl group to the C-5 position. The hydrophenanthrene derivative <B>2</B> was further transformed into 2,3,3a,4,5,9b-hexahydro-7-methoxy-3aβ-methyl-9bα<I>H</I>-1<I>H</I>-benz[<I>e</I>]inden-3β-ol (<B>3</B>). Since the conversion of <B>3</B> into steroidal hormones has already been reported, the present synthesis can be regarded as the synthesis of steroidal hormones from (+)-dehydroabietic acid.
- 公益社団法人 日本化学会の論文
著者
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Yoshinari Takashi
Department Of Biological And Environmental Chemistry Faculty Of Agriculture Tottori University
-
Imai Sachihiko
Department of Chemistry, Faculty of Science, Hiroshima University
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Sunaoka Yasuhiro
Department of Chemistry, Faculty of Science, Hiroshima University
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Matsumoto Takashi
Department of Applied Material Science, Faculty of Integrated Arts and Sciences, University of Tokushima
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