Neuro-otological examinations in nine patients with multiple sclerosis(MS) associated with vertigo and disequilibrium.
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Nine MS patients with vertigo and disequilibrium were neuro-otologically examined.Examination of the vestibulo-oculomotor system revealed that these patients had i) conjugated eye movenents disorder (MLF syndrome), ii) bilateral fixation nystagmus, iii) OKN disorder, iv) ETT disorder, v) vertical positional nystagmus and vertical positioning nystagmus, vi) rebound nystagmus which suggested in the dorsal parts of the brain-stem (i-iii) and in the vermis and nuclei of cerebellum (iv-vi).On auditory examination, the prolongation of the wave III-V IPL and the increased wave ITV amplitude ratio were characteristic findings of ABR. Since the auditory pathway runs in the dorsal parts of the upper brain-stem, the latter components of ABR seemed to be markedly damaged by MS.Neuro-otological examinations appear to be more sensitive than rutine neurological examinations for detecting multi-focal lesions in MS patients with vertigo and disequilibrium.MRI was found to be the most satisfactory technique for diagnosing MS.
- 耳鼻咽喉科臨床学会の論文
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