A case of adenolymphoma. Immunohistological studies.:Immunohistological studies

概要

論文の詳細を見る
A case of adenolymphoma occurred in the left parotid gland of a 60-year old male treated with superficial parotidectomy was described.<BR>The treatment of choice was superficial parotidectomy, but not enucleation of tumor, because of the multicentric development of this tumor, or the risk of facial nerve injury during operative procedures.<BR>Histopathological examination revealed that epithelial tissue was arranged in two-layers of columnar and cuboidal cells with papillary proliferation, and projected into cystic cavities. Interstitial tissue contained lymphoid tissue with several germinal centers.<BR>Immunohistological studies on IgG, IgA, IgM, secretory component (SC), T and B cells were performed and following results were obtained. In the lymphoid tissue, the majority of lymphocytes were B cell and a few T cells were observed beneath the epithelium. The number of IgG-positive cells made it the most predominant isotype in the lymphoid tissue followed by IgA-, and IgM-positive cells. Localization of IgA and SC were observed in some parts of columnar and cuboidal cells of the epithelium as well as in the contents of cystic cavities suggesting the presence of SC-mediated transport mechanism of IgA in adenolymphoma.