Studies on Fatty Acid Esters of Flavins : VI. Incorporation of Riboflavin Part of Riboflavin Tetrabutyrate-2-14C into Flavin Nucleotides in the Organs of Rat

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Riboflavin-2′, 3′, 4′, 5′-tetrabutyrate-2-14C, synthesized from riboflavin-2-14C, was administered to normal rats per os or by injection. At 72 hours after the administration, the radioactivities of FAD, FMN and riboflavin fractions extracted from the liver, kidney, heart, and small intestine were measured. The results show that the same level of specific radioactivities was found in all flavins of these organs. The specific radioactivities in the case of per os administration were at the same level as those in the case of injection. From these results, it was concluded that the riboflavin moiety of the butyrate administered per os or by injection can be incorporated into FMN and FAD of these organs.
日本ビタミン学会の論文