Studies on Myoinositol:IV. Effect of Myoinositol on the Cholesterol Metabolism of Rats Suffering from Experimental Fatty Liver

概要

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The administration of a fat free, low protein diet with no B vitamin supplement to albino rats for 3 weeks resulted in marked fatty livers. When these depleted rats suffering from fatty liver were treated with B vitamins for a week, livers were abnormally swelled and their fats and cholesterols were greatly increased. Such a type of fatty liver, however, was partly cured by administering, besides B vitamins, either myoinositol or choline, and almost completely by administering both of them for a week.A considerable delay was found in the movement of cholesterol from fatty livers to adipose tissues, when compared with that from the livers cured by administration of myoinositol. This may be ascribed to an occurrence of an inhibitory mechanism on cholesterol transport in fatty livers, which is eliminated by the administration of myoinositol.
日本ビタミン学会の論文