Studies on Myoinositol : VII. Removal of Deposited Fats from Dietary Fatty Liver

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概要

• 論文の詳細を見る

• 1. Electron microscopic observations have shown that when dietary fatty liver is induced in rats, the intracellular structure of the liver parenchymal cells is considerably deformed due to depositions of fat droplets in the cytoplasm. Such changes are considerably recovered by treating rats for a week with myoinositol; the reduction of the size and the number of fat droplets is evident and the lamellar structure of the rough-surfaced endoplasmic reticulum becomes distinct.2. Histological comparison of the liver sections before and after the perfusion of the isolated dietary fatty liver indicated that myoinositol, when added to the perfusate, accelerates the movement of fats from the liver to the artificial blood stream. This was confirmed by chemical analysis of the blood before and after the perfusion.3. Similar acceleration of the removal of fats by this cyclitol was observed in the hepatic cellular level regardless of the presence of infiltrated fats in the cytoplasm.

• 日本ビタミン学会の論文

著者

• HASAN Syed

  Institute of Biochemistry Faculty of Medicine, University of Nagoya

• 西垣 郁雄

  Institute of Biochemistry Faculty of Medicine, University of Nagoya

• 八木 国夫

  Institute of Biochemistry, Faculty of Medicine, University of Nagoya

• 小滝 祥

  Institute of Biochemistry, University of Nagoya

• 奥山 澄彦

  Department of Internal Medicine, University of Nagoya

• 伊藤 庄三

  Department of Internal Medicine, University of Nagoya

• 山田 弘三

  Department of Internal Medicine, University of Nagoya

• 山下 和雄

  Department of Anatomy, Faculty of Medicine, University of Nagoya

• 八木 国夫

  Institute of Biochemistry, University of Nagoya

• 西垣 郁雄

  Institute of Biochemistry, University of Nagoya

• 小滝 祥

  Institute of Biochemistry, Faculty of Medicine, University of Nagoya

• 山田 弘三

  Department of Internal Medicine, Faculty of Medicine, Nagoya University

関連論文

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