沖縄における小児のツベルクリン反応追求調査-1-調査成績の概要

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A follow-up survey of tuberculin reaction was carried out in the autumn of 1969, one year after the first Survey, on children in Okinawa, aged 0 to 13 or 14 years (2nd grade of junior high school), who had been perfectly examined at the Tuberculosis Prevalence Survey in 1968. Tuberculin tests were performed on 8, 499 children with attendance rate of 99.5%, and the children whose transverse diameter of induration was 5mm or more, were examined by chest radiograms. On 7, 337 children who had never been vaccinated with B.C.G., changes in the results of tuberculin reaction from 1968 to 1969 were analyzed in relation to several factors such as sex, age, the presence or absence of tuberculous patients in their households, etc. Moreover, the background factors of newly detected TB suspects were studied, and the prevalence of healed lesions on chest radiograms was observed by the degree of tuberculin allergy. The results were as follows: 1) The positive conversion rate by age was 1.16% for 0-4 years, 0.79% for 5-9 years, 3.57% for 10-14 years and 1.67% for the total. Among children with tuberculous patients in their households, the positive conversion rate was 5.5 times higher than that of children without patients. 2) The negative conversion rate by age was 22.86% for 0-4 years, 26.98% for 5-9 years, 18.40% for 10-14 years and 21.16% for the total. Children who were strongly positive in 1968 or who had tuberculous patients in their households, showed lower negative conversion rate. 3) Seven new TB suspects were detected by chest radiograms and five of them were primary tuberculosis with hilar lymphnode swelling. Among them, three were the family member of active-infectious TB patients. 4) Prevalence of healed lesions on chest radiograms increased proportionally to the intensity of tuberculin allergy. The positive conversion rate derived from this survey might be somewhat over-estimate of the infection rate among children in Okinawa, as the negative conversion from the positive reactors without previous BCG vaccination was relatively high. In order to estimate a more reasonable infection rate, it seems to be necessary to develop some new methods considering both negative conversion as well as positive conversion. These problems will be discussed in the next report.
一般社団法人日本結核病学会の論文

沖縄における小児のツベルクリン反応追求調査-1-調査成績の概要

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