化学療法中回腸穿孔を併発した肺結核の1例

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We present a male case with pulmonary tuberculosis who developed ileal perforation during antituberculous therapy. A 30 year-old man was admitted to our department in September 1979. He had a three-month history of night sweating and slight fever. Tubercle bacilli were demonstrated on light microscopy from his sputa. We started treatment using RFP, EB, and INH. Four months after starting treatment he complained of abdominal pain, and laparotomy was performed. We observed ileal perforation with surrounding adhesion. Histopathologic examination of resected ileum and mesenteric lymph nodes showed chronic ulcer and granuloma with Schaumann body in ileal submucosa, and presence of giant cell with asteroid body. There was no foci with caseous necrosis. These findings were also compatible with sarcoidosis, but good response to antituberculous therapy or absence of bilateral hilar lymphadenopathy of the lung lead us to the result of ileal tuberculosis.
日本結核病学会の論文