Carcinoma in pleomorphic adenoma of the parotid gland: Report of a case and immunohistochemical observation.

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A case of carcinoma in pleomorphic adenoma which developed in the deep lobe of the left parotid gland of a 75-year-old Japanese man is described.<BR>The case was clinically prediagnosed as a benign salivary gland tumor; however, examination of excised tissue revealed small areas of adenoid cystic carcinoma invading the capsule and of pleomorphic adenoma comprising almost all the tumor tissue. The surgical procedure choice included complete excision of the tumor tissue with lobectomy of the superficial part of the left parotid gland.<BR>Recurrence or metastasis has not been noted in the one year and 8 months since operation.<BR>The excised material was also examined from an immunohistochemical aspect, using the peroxidase-antiperoxidase method. The staining of S-100 protein, lysozyme, transferrin, secretary component, and keratin showed similar findings as have been already reported.
社団法人日本口腔外科学会の論文