Neuromyelitis Optica in Japanese Sisters
スポンサーリンク
概要
- 論文の詳細を見る
We report cases of Japanese sisters with neuromyelitis optica (NMO). The elder sister was 25, when she was diagnosed with right optic neuritis. After 3 months, she developed left optic neuritis and myelitis. At age 27, she had the second relapse, but she has been free from episodes thereafter. The younger sister was 26, when she was diagnosed with optic neuritis. Thus far, she has 9 relapses, comprising both myelitis and optic neuritis. Both sisters had normal brain MRI scans, longitudinally extensive transverse myelitis over 3 vertebral segments, and positive results for anti-aquaporin-4 antibody (AQAP4Ab). They fulfilled the Wingerchuk criteria for definite NMO. Both sisters shared some immunogenetic factors, but they were not exposed to the same environmental factors after their early twenties. The final disability status was almost the same in both cases, and both showed a very benign course. These data suggest that genetic factors affect the age at onset and environmental factors may affect the frequency of relapse.
著者
-
Hozumi Isao
Department Of Neurology And Geriatrics Gifu University Graduate School Of Medicine
-
Koumura Akihiro
Department of Neurology and Geriatrics, Gifu University Graduate School of Medicine
-
Inuzuka Takashi
Department Of Geriatrics And Neurology School Of Medicine Gifu University
-
Hayashi Yuichi
Department Of Materials Science And Engineering Nagoya Institute Of Technology
-
Yamada Megumi
Department Of Chemistry Graduate School Of Science Tohoku University
-
Moriwaki Hisataka
The First Department Of Internal Medicine Gifu University School Of Medicine
-
Harada Naoko
Department Of Floriculture And Ornamental Horticulture College Of Bioresource Sciences Nihon Univers
-
Sakurai Takeo
Department Of Aeronautical Engineering Faculty Of Engineering Kyoto University
-
Tanaka Yuji
Department Of Applied Chemistry Faculty Of Engineering Kyushu Institute Of Technology
-
Kimura Akio
Department Of Anesthesiology And Intensive Care Kyoto Prefectural University Of Medicine
-
Yoshikura Nobuaki
Department of Neurology and Geriatrics, Graduate School of Medicine, Gifu University, Japan
-
Harada Naoko
Department of Neurology and Geriatrics, Graduate School of Medicine, Gifu University, Japan
-
Moriwaki Hisataka
The First Department of Internal Medicine, Graduate School of Medicine, Gifu University, Japan
関連論文
- Markedly Ring-enhanced Optic Nerves Due to Metastasis of Signet-ring Cell Gastric Carcinoma
- Microarray analysis of the liver in metallothionein-III null mice treated with cadmium
- Resistance of metallothionein-III null mice to cadmium-induced acute hepatotoxicity
- DNA microarray analysis of transcriptional responses of mouse spinal cords to physical exercise(Toxicogenomics/proteomics Report)
- Metallothioneins and Neurodegenerative Diseases
- Serial Monitoring of Basal Metabolic Rate for Therapeutic Evaluation in an Isaacs Syndrome Patient with Chronic Fluctuating Symptoms
- Longitudinal Analysis of Cytokines and Chemokines in the Cerebrospinal Fluid of a Patient with Neuro-Sweet Disease Presenting with Recurrent Encephalomeningitis
- Magnetic Resonance Axillography for Preoperative Diagnosis of the Axillopectoral Muscle (Langer's Axillary Arch): A Case Report
- Anastrozole-Induced Remission of Diaphragmatic Paralysis from Metastatic Breast Cancer Treated with Multiple Prior Therapies
- Comparison of Gene Expression in Breast Cancer Using Laser Capture Microdissection and Quantitative RT-PCR(Prof. K Watanabe Memorial Article)
- Chromosome 3p and breast cancer
- p63 Expression in Normal, Hyperplastic and Malignant Breast Tissues
- Thymidine Phosphorylase is Regulated by Tamoxifen in T47D Breast Cancer Cell Line
- MR-Axillography Oriented Surgical Sampling for Assessment of Nodal Status in the Selection of Patients with Breast Cancer for Axillary Lymph Nodes Dissection
- A Mathematical Model of Axillary Lymph Node Involvement Considering Lymph Node Size in Patients with Breast Cancer
- Correlation between Nuclear Grade and Biological Prognostic Variables in Invasive Breast Cancer
- Novel polymorphisms of prostate-specific antigen (PSA) gene associated with PSA mRNA expression in breast cancer
- Thymidine Phosphorylase Expression Correlates with Tumor Differentiation and Bcl-2 in Invasive Breast Cancer
- Expression of Bcl-2, but not Bax, correlates with estrogen receptor status and tumor proliferation in invasive breast carcinoma
- Evaluation of Axillary Lymph Node Status in Breast Cancer with MRI
- Extensive intraductal component (EIC) and estrogen receptor (ER) status in breast cancer
- Clinical Outcome of immediate Breast Reconstruction Using a Silicone Gel-filled Implant after Nipple-preserving Mastectomy
- A PURKINJE CELL-SPECIFIC PROTEIN (SPOT 35 PROTEIN) SHOWING WIDE DISTRIBUTION IN THE ENDOCRINE SYSTEM OF SOME MAMMALS. AN IMMUNOHISTOCHEMICAL STUDY
- Dendritic cell immunotherapy for patients with metastatic renal cell carcinoma : University of Tokyo experience
- Cut-Offs for Screening Prolonged QT Intervals From Fridericia's Formula in Children and Adolescents
- Peripheral nerve avulsion injuries as experimental models for adult motoneuron degeneration
- PE-413 Association Between the Accumulation of Cardiovascular Risk Factors and Adipokine or Individual Risk Factor Levels in Adolescent Volunteers(PE069,Preventive Medicine/Epidemiology/Education 2 (H),Poster Session (English),The 73rd Annual Scientific M
- Association Between the Number of Cardiovascular Risk Factors and Each Risk Factor Level in Elementary School Children
- Prevalence and Time of Appearance of Brugada Electrocardiographic Pattern in Young Male Adolescents From a 3-year Follow-up Study (Arrhythmia, Diagnosis/Pathophysiology/EPS 8 (A), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- OJ-260 Prevalence and Age of Appearance of the Brugada Type Electrocardiogram in Young Adolescents(ECG/Body Surface Potential Mapping/Holter 3 (A) : OJ30)(Oral Presentation (Japanese))
- EXPONENTIAL CORRECTION OF QT INTERVAL TO MINIMIZE THE EFFECT OF THE HEART RATE IN CHILDREN
- Sodium Bicarbonate Infusion Test : A New Method for Evaluating Parathyroid Function
- Pathologic changes of glial cells in murine model of Niemann-Pick disease type C : Immunohistochemical, lectin-histochemical and ultrastructural observations
- Usefulness of novel imaging modalities in diagnosis of focal nodular hyperplasia of the liver
- Cellular Biological Differnces Between Human Myeloma Cell Lines KMS-12-PE and KMS-12-BM Established From a Single Patient
- Steroid-Responsive Limbic Encephalitis
- Angiogenesis and Metastasis Marker of Human Tumors
- Adipokines and the Prediction of the Accumulation of Cardiovascular Risk Factors or the Presence of Metabolic Syndrome in Elementary School Children
- Wakame Seaweed Suppresses the Proliferation of 7,12-Dimethylhenz(α)-anthracene-induced Mammary Tumors in Rats
- Asymmetric Sidebands of Low Frequency Waves in a Current Carrying Plasma
- Excitation and Damping of Continuous Pseudo Acoustic and Ion Waves in a Plasma
- Ballistic Phase Mixing of Continuous Pseudo Waves in a Plasma
- Ion Wave Damping in a Nonuniform Plasma
- Ion Wave Damping in Nonuniform Plasma
- Tensile Bond Strength of a Newly Developed One-bottle Self-etching Resin Bonding System to Various Dental Substrates
- Nutrient limitation of the primary production of phytoplankton in Lake Baikal
- Venous congestive myelopathy of the cervical spinal cord : An autopsy case showing a rapidly progressive clinical course
- Therapeutic Effect of Balloon-occluded Retrograde Transvenous Obliteration on Portal-systemic Encephalopathy in Patients with Liver Cirrhosis
- HBME-1 Immunostaining in Thyroid Tumors Especially in Follicular Neoplasm
- Successful Surgical Treatment of a Solitary Parapharyngeal Metastasis from Thyroid Cancer, Using the Mandibular Swing-Transcervical Approach: Report of a Case
- Incidentally Discovered Adrenocortical Adenomas Are Not Fully Nonfunctioning: lmmunohistochemical and Dispersed Adrenocortical Cell Study
- Modulation of organic anion transporting polypeptide 1 and multidrug resistance protein 3 expression in the liver and kidney of Gunn rats
- Synthesis and Characterization of Collagenous Peptides Cross-Linked at Their Amino and Carboxy Termini
- Effects of Shear Stress on the Self-Assembly Process of Elastomeric Polypeptides
- Synthesis and Characterization of Peptide-Surfactants Using Elastin Repeating Unit
- Fluorescence Energy Transfer to Tailed Acridine Oranges from Pyrene Excimer in Four α-Helix Bundle 53-peptide
- Indirect Calorimetry and Anthropometry to Estimate Energy Metabolism in Patients with Liver Cirrhosis
- Care and care-education system for elderly people with dementia in Japan and Sweden
- Nocturnal energy and BCAA supplementation in patients with liver cirrhosis
- Cerebellar Ataxia and Peripheral Neuropathy due to Chronic Bromvalerylurea Poisoning
- Energies of Low-lying Excited States and Reactivity of Giant Polycyclic Aromatic Hydrocarbons with a Hole Inside
- Enhancement of Plant Stem Growth by Flocculation of the Antibiotic-producing Bacterium, Pseudomonas fluorescens S272,on the Roots
- Effect of Zinc-Carnosine Chelate Compound on Muscle Function in Mdx Mouse
- Type II Citrullinemia in an Elderly Patient Treated with Living Related Partial Liver Transplantation
- Long-term Survival of a Patient with Splenic Angiosarcoma after Resection, High-dose Chemotherapy, and Autologous Peripheral Blood Stem Cell Transplantation
- Indirect Calorimetry and Anthropometry to Estimate Energy Metabolism in Patients with Liver Cirrhosis
- Balloon Catheter Test in Patients with Atrial Septal Defect and Patent Ductus Arteriosus
- Surveillance and Follow-up of Patients with Implanted Cardiac Pacemaker by Telephone Transmission
- Ulcerative Colitis in Female Siblings with an Identical Human Leukocyte Antigen Haplotype (A24, Bw52, DR52 and DQw1)
- Myelofibrosis Successfully Treated with Prednisolone in a Patient with Pachydermoperiostosis
- Diffuse Skeletal Muscles Uptake of [18F] Fluorodeoxyglucose on Positron Emission Tomography in Primary Muscle Peripheral T-cell Lymphoma
- Effects of Hypertonic Mannitol on Renal Function in Open Heart Surgery
- Pulmonary Shunting during Venovenous Bypass
- Pulsatile Venous Flow in Extracorporeal Circulation
- Relation between Hydrogen Storage Properties and Structure of Nd-Co-B Amorphous Alloys
- Heat-Up of Rotating Stratified Fluid
- Flow in Close Binary Systems
- Flow past a Bent Flat Plate with an Unsymmetric Dead Air at Mach Number 1
- Steady Two-Dimensional Channel Flow of an Incompressible Perfect Fluid with Small Electric Conductivity in the Presence of Nonuniform Magnetic Fields
- Two-dimensional Flow of an Ideal Gas with Small Electric Conductivity past a Thin Profile
- Spin Down of Boussinesq Fluid in a Circular Cylinder
- High Subsonic Flow with Normal Shock Wave at Nearly Critical Mach Number
- Correction to the Paper "Two-dimensional Flow of an Ideal Gas with Small Electric Conductivity past a Thin Profile"
- Analysis of Dynamic Characteristics of Spiral-Grooved Journal Bearing with Considering Cavitation Occurrence
- The Flow past a Flat Plate accompanied with an Unsymmetric Dead Air at Mach Number 1
- Effect of the Plasma Impedance on the Time Variation of the Inverse Pinch
- CLINICAL DATA OF NUTRITIONAL TREATMENT FOR LIVER CIRRHOSIS
- Neuromyelitis Optica in Japanese Sisters
- Chronic Neutrophilic Leukemia with Congenital Robertsonian Translocation Successfully Treated with Allogeneic Bone Marrow Transplantation in a Young Man
- Late-onset Patients with Sporadic Amyotrophic Lateral Sclerosis in Japan have a Higher Progression Rate of ALSFRS-R at the Time of Diagnosis
- Effects of Experimental Chronic Volume Overloading on Left Ventricular Contractility and Compliance
- The Combined Effects of All-Trans Retinoic Acid and Granulocyte Colony-Stimulating Factor as a Differentiation Induction Therapy for Acute Promyelocytic Leukemia.
- Intracranial Calcification in a Patient with HDR Syndrome and a GATA3 Mutation
- A Male Case of Synchronous Double Cancers of the Breast and Prostate.
- Immunoproliferative Small Intestinal Disease with Protein Loss Complicated with Duodenal T Cell Lymphoma during Progression
- Therapeutic Effect of Balloon-occluded Retrograde Transvenous Obliteration on Portal-systemic Encephalopathy in Patients with Liver Cirrhosis.
- Pure Erythroid Leukemia with Hemophagocytosis
- S7. Sonication-time and impurity effects of sonoluminescence from Na atom in surfactant solutions(Oral Presentation)
- Modulation of Collagen Synthesis and Degradation by Retinoids and Cytokines in 3T3 L1 Preadipocytes.
- Nutritional status and quality of life in current patients with liver cirrhosis as assessed in 2007-2011