Adipokines and the Prediction of the Accumulation of Cardiovascular Risk Factors or the Presence of Metabolic Syndrome in Elementary School Children
スポンサーリンク
概要
- 論文の詳細を見る
Background Information is limited about how adipokines predict the accumulation of cardiovascular (CV) risk factors or the presence of metabolic syndrome (MS) in children. Methods and Results The subjects were 321 children (200 boys and 121 girls; 109 normal and 212 obese) aged 6-12 years. Obesity was defined as a body mass index of ≥ the 95^<th> percentile for age and sex. MS was defined by using the newly established Task Force criteria. The levels of the adipokines-adiponectin, leptin, ghrelin, high sensitive C-reactive protein (CRP) and resistin-were measured. Regression analyses revealed that high leptin levels were predictive of the accumulation of CV risk factors in normal weight, obese, and entire (normal weight and obese) group of subjects. High CRP in the normal weight group and low adiponectin in the obese and the entire groups were also independently predictive of the accumulation of risk factors. A high leptin level was solely predictive of the presence of MS in obese and entire groups. Conclusions Leptin was the most sensitive marker for predicting the accumulation of CV risk factors and the presence of MS in elementary school children. Primary prevention is important because both leptin and adiponectin levels abruptly worsened when children obtained any 1 risk factor.
- 社団法人日本循環器学会の論文
- 2008-10-20
著者
-
Tanaka Yuji
Department of Molecular and Functional Genomics, Center for Integrated Research in Science, Shimane
-
Yoshinaga Masao
Department of Pediatrics, National Hospital Organization Kagoshima Medical Center
-
Yoshinaga Masao
Division Of Pediatrics Graduate School Of Medical And Dental Sciences Kagoshima University
-
Yoshinaga Masao
Kagoshima Med Ctr
-
Yoshinaga Masao
Kagoshima Medical Center
-
WADA Akihiro
Department of Bacteriology, Institute of Tropical Medicine, Nagasaki University
-
Tanaka Yuji
Second Department Of Internal Medicine Kagoshima University
-
Tanaka Yuji
Department Of Electronics Faculty Of Engineering Nagoya University
-
Wada Akihiro
Kagoshima Medical Center
-
Wada Akihiro
Department Of Bacteriology Institute Of Tropical Medicine Nagasaki University
-
Sameshima Koji
Kagoshima City Medical Association
-
Sameshima Koji
Department Of Pediatrics Kagoshima City Medical Association Hospital
-
Yoshinaga Masao
Department Of Pediatrics Faculty Of Medicine Kagoshima University
-
Hashiguchi Jun
Kagoshima City Medical Association
-
Tahara Hirofumi
Kagoshima City Medical Association
-
Kono Yasuko
Kagoshima City Medical Association
-
吉永 正夫
Department Of Pediatrics National Hospital Organization Kagoshima Medical Center
-
Tanaka Yuji
Department Of Applied Chemistry Faculty Of Engineering Kyushu Institute Of Technology
-
Matsuda Yoshio
Department Of Obstetrics And Gynecology Maternal And Perinatal Center Maternal Division Tokyo Women's Medical University
関連論文
- Gateway Binary Vectors with the Bialaphos Resistance Gene, bar, as a Selection Marker for Plant Transformation
- Cut-Offs for Screening Prolonged QT Intervals From Fridericias Formula in Children and Adolescents
- Markedly Ring-enhanced Optic Nerves Due to Metastasis of Signet-ring Cell Gastric Carcinoma
- 緑膿菌由来のIL-8誘導蛋白の生物学的活性とその臨床的意義
- FRS-092 Infective Endocarditis in Pediatric Patients and Adults with Congenital Heart Disease : Japanese Nationwide Survey(Preventive Medicine in Cardiovascular Disease (H) : FRS11)(Featured Research Session (English))
- 2 Infective Endocarditis in Pediatrics and Adults with Congenital Heart Disease(Prophylaxis of Infectious Endocarditis-Why AHA guideline changed?-,Symposium 18 (SY-18) (IHD),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- Causative Organism Influences Clinical Profile and Outcome of Infective Endocarditis in Pediatric Patients and Adults With Congenital Heart Disease
- Survey of Prophylaxis and Management of Infective Endocarditis in Patients With Congenital Heart Disease : Japanese Nationwide Survey
- Serial Monitoring of Basal Metabolic Rate for Therapeutic Evaluation in an Isaacs Syndrome Patient with Chronic Fluctuating Symptoms
- Longitudinal Analysis of Cytokines and Chemokines in the Cerebrospinal Fluid of a Patient with Neuro-Sweet Disease Presenting with Recurrent Encephalomeningitis
- Dendritic cell immunotherapy for patients with metastatic renal cell carcinoma : University of Tokyo experience
- 5病日未満で診断された川崎病患児の冠動脈瘤危険因子に関する検討
- Cut-Offs for Screening Prolonged QT Intervals From Fridericia's Formula in Children and Adolescents
- Interval Representative of Transmural Dispersion of Repolarization in Children and Young Adolescents With Congenital Long QT Syndrome
- PJ-741 Risk Factors for Fortality During Infective Endocarditis in Pediatric and Adult Patients with Congenital Heart Diseases(Congenital heart disease/Kawasaki's disease-3 (M) PJ126,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting
- PE-413 Association Between the Accumulation of Cardiovascular Risk Factors and Adipokine or Individual Risk Factor Levels in Adolescent Volunteers(PE069,Preventive Medicine/Epidemiology/Education 2 (H),Poster Session (English),The 73rd Annual Scientific M
- Association Between the Number of Cardiovascular Risk Factors and Each Risk Factor Level in Elementary School Children
- Suspected Takotsubo Cardiomyopathy Caused by Withdrawal of Bupirenorphine in a Child
- Four Cases of Kawasaki Syndrome Complicated With Myocarditis
- Prevalence and Time of Appearance of Brugada Electrocardiographic Pattern in Young Male Adolescents From a 3-year Follow-up Study (Arrhythmia, Diagnosis/Pathophysiology/EPS 8 (A), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Predictive Factors in the Success of Intervention to Treat Obesity in Elementary School Children
- Heart Rate Variability and Ambulatory Blood Pressure Monitoring in Young Patients With Hypertrophic Cardiomyopathy
- OJ-260 Prevalence and Age of Appearance of the Brugada Type Electrocardiogram in Young Adolescents(ECG/Body Surface Potential Mapping/Holter 3 (A) : OJ30)(Oral Presentation (Japanese))
- Who Is at Risk for Cardiac Events in Young Patients With Long QT Syndrome?
- Prevalence of Sudden Cardiac Death among Young Adolescents in Kagoshima City : What Is the Future Direction?
- 保育園児の鼻咽喉における呼吸器感染症病原菌の保菌状況
- Effect of age and overweight on the QT interval and the prevalence of long QT syndrome in children
- Bilateral Coronary Artery Dilatation in a Child With Noonan Syndrome
- Correction of the QT Interval in Children
- Screening for QT Prolongation Using a New Exponential Formula
- EXPONENTIAL CORRECTION OF QT INTERVAL TO MINIMIZE THE EFFECT OF THE HEART RATE IN CHILDREN
- Risk factors for persistence of pulmonary arterial branch stenosis in neonates and young infants
- Sepsis and meningitis due to penicillin-resistant viridans streptococci in neutropenic children
- High Molecular Weight Factor in FCS Inhibits Helicobacter pylori VacA-Binding to Its Receptor, RPTPβ, on AZ-521
- Helicobacter pylori vacuolating cytotoxin, VacA
- Induction of Active Invagination of Plasma Membranes by Helicobacter pylori Cytotoxin, VacA, in Cultured Gastric Cells. An Immunoelectron Microscopic Study.
- Sodium Bicarbonate Infusion Test : A New Method for Evaluating Parathyroid Function
- A case of adrenal and cephalhematoma abscesses caused by Escherichia coli after forceps delivery
- Immune response to a laminin-binding protein (Lmb) in group A streptococcal infection
- Bronchial polyp in a child with endobronchial tuberculosis under fiberoptic bronchoscopic observation
- Adolescent Obesity Adversely Affects Blood Pressure and Resting Heart Rate
- Inverted duplication/deletion of the short arm of chromosome 8 in two patients with tetralogy of Fallot
- Usefulness of novel imaging modalities in diagnosis of focal nodular hyperplasia of the liver
- Purification and Some Properties of Human-β- Defensin-2 (HBD-2) Inducing Factor from Salmonella enteritidis
- Method of Gene Delivery into Cells Using Dendritic Poly (L-Lysine)s
- DNA-Binding Abilities of Cationic α-Helix Peptides and Their Transfection Abilities into Cells
- Interaction of Amphiphilic α-Helical Peptides with Phospholipid Membrane and Their DNA Binding Ability
- Circulation Immune Complexes and Granulocytes Chemotaxis in Kawasaki Disease : THE 8TH CONFERENCE ON PRVENTION FOR RHEUMATIC FEVER AND RHEUMATIC HEART DISEASE
- Helicobacter pylori Vacuolating Cytotoxin, VacA, Is Responsible for Gastric Ulceration
- High-Level Expression of Heat-Stable Enterotoxin (ST) Receptor with Exchange of the Signal Peptide in Baculovirus/Insect Cell System
- PJ-079 Percentile Values of Markers for Individual Metabolic Syndrome in Japanese Adolescents(Diabetes/Obesity/Metabolic syndrome(09)(H),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- Adipokines and the Prediction of the Accumulation of Cardiovascular Risk Factors or the Presence of Metabolic Syndrome in Elementary School Children
- OJ-048 Risk Factors for Deceased Carotid Artery Elasticity in Healthy Adolescent Volunteers(Atherosclerosis, clinical(03)(IHD),Oral Presentation(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- Wakame Seaweed Suppresses the Proliferation of 7,12-Dimethylhenz(α)-anthracene-induced Mammary Tumors in Rats
- Asymmetric Sidebands of Low Frequency Waves in a Current Carrying Plasma
- Excitation and Damping of Continuous Pseudo Acoustic and Ion Waves in a Plasma
- Ballistic Phase Mixing of Continuous Pseudo Waves in a Plasma
- Ion Wave Damping in a Nonuniform Plasma
- Ion Wave Damping in Nonuniform Plasma
- Nutrient limitation of the primary production of phytoplankton in Lake Baikal
- Evaluation of angiotensin II and endothelin-1 induced myocardial fibrosis in congestive heart failure by using picrosirius red staining method
- HBME-1 Immunostaining in Thyroid Tumors Especially in Follicular Neoplasm
- Successful Surgical Treatment of a Solitary Parapharyngeal Metastasis from Thyroid Cancer, Using the Mandibular Swing-Transcervical Approach: Report of a Case
- Incidentally Discovered Adrenocortical Adenomas Are Not Fully Nonfunctioning: lmmunohistochemical and Dispersed Adrenocortical Cell Study
- Modulation of organic anion transporting polypeptide 1 and multidrug resistance protein 3 expression in the liver and kidney of Gunn rats
- Damage mechanics approach to nonlinear behavior of FRP laminates with cracking layers
- Synthesis and Characterization of Collagenous Peptides Cross-Linked at Their Amino and Carboxy Termini
- Acute theumatic fever and poststreptococcal acute glomerulonephritis caused by T serotype 12 Streptococcus
- Effects of Shear Stress on the Self-Assembly Process of Elastomeric Polypeptides
- Synthesis and Characterization of Peptide-Surfactants Using Elastin Repeating Unit
- Fluorescence Energy Transfer to Tailed Acridine Oranges from Pyrene Excimer in Four α-Helix Bundle 53-peptide
- Construction of Four α-Helix Bundle Structure with L- and D-Amino Acid Segments
- The Building of Antiparallel Four α-Helix Bundle Structure with a Pair of Pyrenylalanines on a Cyclic Pseudo-peptide Template
- Screening of a Mutant Plasmid with High Expression Efficiency of GC-Rich leuB Gene of an Extreme Thermophile, Thermus thermophilus, in Escherichia coli
- Equivalent Circuit Model and Magnetic Field Diffusion Equation in the Tokamak Simulation
- Equilibrium in a Multipole Tokamak
- An HTLV-I carrier with Graves' disease followed by uveitis: isolation of HTLV-I from thyroid tissue
- Cytotoxicity of Antiserum Sensitized to Hemolytic Streptococcal M Protein Fraction on Cultured Myocardial Cells : Proceedings of the 5th Conference on Prevention for Rheumatic Fever and Rheumatic Heart Disease
- Low-Threshold Photopumped Distributed Feedback Plastic Laser Made by Replica Molding
- Photopumped Organic Solid-State Dye Laser with a Second-Order Distributed Feedback Cavity : Optics and Quantum Electronics
- Mid-term mortality of very elderly patients with acute myocardial infarction with or without coronary intervention
- Radiofrequency Catheter Ablation with the Use of a Noncontact Mapping System for Ventricular Tachycardia Originating from the Aortic Sinus Cusp : A Case Report
- Lipidation of the Collagen Model Peptide to Make Peptide-Surfactant
- Two Types of Cation Binding Sites on Elastomeric Polypeptides : Effects on Self-Assembly Process and Elastomeric Functions
- New apparatuses for cultivation of appendicularians
- Design of the Triple-Stranded Coiled-Coil Structure Incorporating Ion Pair Residues in the Hydrophobic Core
- Study of Antibody Response to 4 Streptococcal Antigens in Rheumatic Fever and Kawasaki Disease with or without Cardiovascular Lesions : THE 11th CONFERENCE ON PREVENTION FOR RHEUMATIC FEVER AND RHEUMATIC HEART DISEASE
- Expression of Somatostatin Receptor and Effects of Somatostatin Analog on Pancreatic Endocrine Tumors
- Gateway Binary Vectors with the Bialaphos Resistance Gene, bar, as a Selection Marker for Plant Transformation
- Development of a Series of Gateway Binary Vectors Possessing a Tunicamycin Resistance Gene as a Marker for the Transformation of Arabidopsis thaliana
- Where are the eggs of the Pacific saury, Cololabis saira?
- Host-Guest Study of Collagen Model Peptide with Pipecolic Acid
- Synthesis and Characterization of Collagen Model Peptides with A Pyrene Group at the Amino-Terminal
- Two Sec13p Homologs, AtSec13A and AtSec13B, Redundantly Contribute to the Formation of COPII Transport Vesicles in Arabidopsis thaliana
- Synthesis and Characterization of Antimicrobial Peptide Surfactants with Dendritic Lysine Groups
- 1978年から2007年の日本における小児肥満の頻度
- Resonant Oscillation in a PIG Discharge
- The QT Intervals in Infancy and Time for Infantile ECG Screening for Long QT Syndrome
- Guidelines for Indication and Management of Pregnancy and Delivery in Women With Heart Disease (JCS 2010) : Digest Version
- Genetic Background of Catecholaminergic Polymorphic Ventricular Tachycardia in Japan