Heart Rate Variability and Ambulatory Blood Pressure Monitoring in Young Patients With Hypertrophic Cardiomyopathy
スポンサーリンク
概要
- 論文の詳細を見る
Background Sudden cardiac death commonly occurs in young patients with hypertrophic cardiomyopathy (HCM); however, their heart rate variability (HRV) and blood pressure (BP) response to daily life activities is not well known. Methods and Results HRV and ambulatory BP monitoring were performed in 20 patients (age range: 7-21 years) and 57 age-matched healthy volunteers (age range: 10-22 years). Time domain variables and spectral data were obtained at hourly intervals throughout the day. To determine the BP response to daily life activities, the ratios of the mean BP and pulse pressure in the morning, afternoon, and night to those during sleeping were calculated. The association between the BP level and HRV was also evaluated. The HCM patients showed significantly increased sympathovagal imbalance and decreased parasympathetic activity in the early morning, around noon, and in the early evening. This abnormality was independent of cardiac symptoms. Symptomatic patients showed a significantly lower systolic BP response in the morning, and a higher incidence of dissociation between sympathetic activity and BP response than asymptomatic patients. Conclusion An abnormal BP response in the presence of impaired HRV appears to be predictive for cardiac events in young patients with HCM.
- 社団法人日本循環器学会の論文
- 2004-07-20
著者
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NOMURA Yuichi
Department of Pediatrics, Preventive Medicine, Graduate School of Medical and Dental Sciences, Kagos
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EGUCHI Taisuke
Department of Pediatrics, Preventive Medicine, Graduate School of Medical and Dental Sciences, Kagos
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KAWANO Yoshifumi
Department of Pediatrics, Preventive Medicine, Graduate School of Medical and Dental Sciences, Kagos
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Nishi Junichiro
Department of Cardiology, Saiseikai Futsukaichi Hospital
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Yoshinaga Masao
Department of Pediatrics, National Hospital Organization Kagoshima Medical Center
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Fukushige Toshiro
Department of Pediatrics, Prefectural Hokusatsu Hospital
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Yoshinaga Masao
Division Of Pediatrics Graduate School Of Medical And Dental Sciences Kagoshima University
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Yoshinaga Masao
Kagoshima Med Ctr
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Yoshinaga Masao
Kagoshima Medical Center
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Fukushige Toshiro
Division Of Pediatrics Graduate School Of Medical And Dental Sciences Kagoshima University
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柳 貞光
Department Of Pediatrics Kagoshima City Medical Association Hospital
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Nomura Yuichi
Department Of Pediatrics Preventive Medicine Graduate School Of Medical And Dental Sciences Kagoshim
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Nomura Yuichi
Department Of Pediatrics Kagoshima University Faculty Of Medicine
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Tanaka Yuji
Second Department Of Internal Medicine Kagoshima University
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Nomura Yuichi
Division Of Pediatrics Graduate School Of Medical And Dental Sciences Kagoshima University
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Nishi J
Division Of Pediatrics Graduate School Of Medical And Dental Sciences Kagoshima University
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TOKUDA Koichi
Department of Electronic Chemistry, Interdisciplinary Graduate School of Science and Engineering, To
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Fusazaki Naoki
Fukuoka Children's Hospital
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Shimago Atsushi
Department of Pediatrics, Graduate School of Medical and Dental Sciences, Kagoshima University
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Kono Yukiharu
Department of Pediatrics, Graduate School of Medical and Dental Sciences, Kagoshima University
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Yanagi Sadamitsu
Department of Pediatrics, Graduate School of Medical and Dental Sciences, Kagoshima University
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Horigome Hitoshi
University of Tsukuba
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Tanaka Yuji
Kyushu National Cardiovascular Center
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Matsuoka Yuji
Matsuoka Clinic
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Miyata Koichiro
Department of Pediatrics, Graduate School of Medical and Dental Sciences, Kagoshima University
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Eguchi Taisuke
Department Of Pediatrics Preventive Medicine Graduate School Of Medical And Dental Sciences Kagoshim
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Eguchi Taisuke
Department Of Pediatrics Kagoshima University Faculty Of Medicine
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Nishi Junichiro
Department Of Cardiology Saiseikai Futsukaichi Hospital
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Nishi Junichiro
Department Of Pediatrics Kagoshima University Graduate School Of Medical And Dental Sciences
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Shimago Atsushi
Department Of Pediatrics Graduate School Of Medical And Dental Sciences Kagoshima University
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Shimago Atsushi
Department Of Pediatrics Faculty Of Medicine Kagoshima University
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Tokuda Koichi
Department Of Pediatrics Kagoshima University Graduate School Of Medical And Dental Sciences
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Tokuda Koichi
Department Of Electrical Engineering And Electronics Seikei University
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Kawano Yoshifumi
Department Of Pediatrics Preventive Medicine Graduate School Of Medical And Dental Sciences Kagoshim
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Kawano Yoshifumi
Department Of Pediatrics Graduate School Of Medical And Dental Sciences Kagoshima University
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Fukushige Toshiro
Department Of Pediatrics Prefectural Hokusatsu Hospital
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Kono Yukiharu
Department Of Pediatrics Izumi City Hospital
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Kono Yukiharu
Department Of Pediatrics Kagoshima University Graduate School Of Medical And Dental Sciences
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野村 裕一
Department Of Pediatrics Faculty Of Medicine Kagoshima University
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Miyata Koichiro
Department Of Pediatrics Graduate School Of Medical And Dental Sciences Kagoshima University
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Miyata K
Department Of Pediatrics Faculty Of Medicine Kagoshima University
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Miyata Koichiro
Department Of Pediatrics Faculty Of Medicine Kagoshima University
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Miyata Koichiro
Kagoshima Children's Hospital
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Yoshinaga Masao
Department Of Pediatrics Faculty Of Medicine Kagoshima University
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野村 裕一
Department Of Pediatrics Preventive Medicine Graduate School Of Medical And Dental Sciences Kagoshim
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Yanagi Sadamitsu
Departments Of Pediatrics Kagoshima Medical Association Hospital:departments Of Pediatrics Izumi Cit
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Horigome Hitoshi
Department Of Pediatrics School Of Medicine University Of Tsukuba
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Manago Kunihiro
Department Of Pediatrics Kagoshima University Graduate School Of Medical And Dental Sciences
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Horigome Hitoshi
Department Of Child Health Graduate School Of Comprehensive Human Sciences University Of Tsukuba
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Miyata Koichiro
Kagoshima Univ. Graduate School Of Medical And Dental Sci. Kagoshima Jpn
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Matsuda Yoshio
Department Of Obstetrics And Gynecology Maternal And Perinatal Center Maternal Division Tokyo Women's Medical University
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Kawano Yoshifumi
Division Of Pediatrics Graduate School Of Medical And Dental Sciences Kagoshima University
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Yanagi Sadamitsu
Department Of Cardiology Kanagawa Children's Medical Center
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Kawano Yoshifumi
Department of Child Health, Graduate School of Comprehensive Human Sciences, University of Tsukuba
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