Cytotoxicity of Antiserum Sensitized to Hemolytic Streptococcal M Protein Fraction on Cultured Myocardial Cells : Proceedings of the 5th Conference on Prevention for Rheumatic Fever and Rheumatic Heart Disease
スポンサーリンク
概要
- 論文の詳細を見る
We have studied cytotoxicity of antisera of monkeys sensitized to streptococcal M protein fraction, which was prepared by the method of Lancefield et al., on cultured myocardial cells. These antisera exerted a significantly higher cytotoxic effect on the myocardial cells than normal monkey sera, and this cytotoxic effect seemed to be organ-specific. In the presence of normal monkey lymphocytes, the antisera had a cytotoxic effect on myocardial cells, but normal sera in the presence of normal monkey lymphocytes had no cytotoxic effects. These data suggest that M protein fraction of hemolytic streptococcus plays an important role in the pathogenesis of rheumatic carditis.
- 社団法人日本循環器学会の論文
- 1981-12-20
著者
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Yoshinaga Masao
Department of Pediatrics, National Hospital Organization Kagoshima Medical Center
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Miyata Koichiro
Department of Pediatrics, Graduate School of Medical and Dental Sciences, Kagoshima University
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Miyata Koichiro
Department Of Pediatrics Graduate School Of Medical And Dental Sciences Kagoshima University
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Miyata K
Department Of Pediatrics Faculty Of Medicine Kagoshima University
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Miyata Koichiro
Department Of Pediatrics Faculty Of Medicine Kagoshima University
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Miyata Koichiro
Kagoshima Children's Hospital
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Yoshinaga Masao
Department Of Pediatrics Faculty Of Medicine Kagoshima University
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TERAWAKI Tamotsu
Department of Pediatrics, Faculty of Medicine, Kagoshima University
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HOKONOHARA MASASHI
Department of Pediatrics, Faculty of Medicine, Kagoshima University
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Terawaki Tamotsu
Department Of Pediatrics Faculty Of Medicine Kagoshima University
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Terawaki Tamotsu
Department Of Pediatrics Faculty Of Medicine Kagoshoima University
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Hokonohara Masashi
Department Of Nursing School Of Health Science Faculty Of Medicine Kagoshima University
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Hokonohara Masashi
Department Of Pediatrics Faculty Of Medicine Kagoshima University
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吉永 正夫
Department Of Pediatrics National Hospital Organization Kagoshima Medical Center
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Manago Kunihiro
Department Of Pediatrics Kagoshima University Graduate School Of Medical And Dental Sciences
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