The Effects of M-protein Fraction of Hemolytic Streptococci on Embryonic Heart in the Rat : THE 9th CONFERENCE ON PREVENTION FOR RHEUMATIC FEVER AND RHEUMATIC HEART DISEASE

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概要

• 論文の詳細を見る

• Wistar rats were administered M-protein fraction (MP) of group A type 12 hemolytic streptococci on day 9 of gestation. When 9 mg/kg of MP was injected, the incidence of malformations was 11.8%, and the incidence of cardiovascular malformations was 7.9%. The main malformations were ventricular septal defect, microphthalmia, and hydrocephaly. Light and electron microscopic studies revealed no myocarditis nor endocarditis in either the maternal or fetal heart. Fluorescent antibody technique demonstrated no immunological cross-reaction between MP and rat heart tissue. the results suggest that MP is slightly teratogenic in the rat.

• 社団法人日本循環器学会の論文
• 1985-12-20

著者

• YAMAMOTO Eiji

  Departmetn of Information Science, Okayama University Science

• Ono S

  Department Of Pediatrics Faculty Of Medicine Kagoshima University

• Ono Seigo

  Department Of Coloproctological Surgery Juntendo University School Of Medicine

• Miyata Koichiro

  Department of Pediatrics, Graduate School of Medical and Dental Sciences, Kagoshima University

• KAWAKAMI KIYOSHI

  Department of Pediatrics, Faculty of Medicine, Kagoshima University

• Kawakami Kiyoshi

  Department Of Pediatrics Faculty Of Medicine Kagoshoima University

• Kawakami Kiyoshi

  Department Of Pediatrics Faculty Of Medicine Kagoshima University

• Kawakami K

  Natioual Institute Of Sericultural And Entomological Science

• Miyata Koichiro

  Department Of Pediatrics Graduate School Of Medical And Dental Sciences Kagoshima University

• Miyata K

  Department Of Pediatrics Faculty Of Medicine Kagoshima University

• Miyata Koichiro

  Department Of Pediatrics Faculty Of Medicine Kagoshima University

• Miyata Koichiro

  Kagoshima Children's Hospital

• JITOSHO Tamotsu

  Department of Pediatrics, Faculty of Medicine, Kagoshima University

• TERAWAKI Tamotsu

  Department of Pediatrics, Faculty of Medicine, Kagoshima University

• TAKESUE TETSUO

  Department of Pediatrics, Faculty of Medicine, Kagoshoima University

• MUNAKATA SHUZO

  Department of Pediatrics, Faculty of Medicine, Kagoshoima University

• Kawakami Kiyoshi

  Department Of Hematology/oncology Osaka Medical Center And Research Institute For Maternal And Child

• Yamamoto Eiji

  Department Of Pediatrics Faculty Of Medicine Kagoshima University

• Takesue Tetsuo

  Department Of Pediatrics Faculty Of Medicine Kagoshoima University

• Munakata Shuzo

  Department Of Pediatrics Faculty Of Medicine Kagoshoima University

• Terawaki Tamotsu

  Department Of Pediatrics Faculty Of Medicine Kagoshima University

• Terawaki Tamotsu

  Department Of Pediatrics Faculty Of Medicine Kagoshoima University

• Jitosho Tamotsu

  Department Of Pediatrics Faculty Of Medicine Kagoshima University

• Ono Seigo

  Department Of Coloproctological Surgery Juntendo University Faculty Of Medicine

• Yamamoto Eiji

  Department Of Industrial Mechanical Engineering

• Manago Kunihiro

  Department Of Pediatrics Kagoshima University Graduate School Of Medical And Dental Sciences

• Kawakami Kiyoshi

  Department Of Biology Jichi Medical School

• Miyata Koichiro

  Kagoshima Univ. Graduate School Of Medical And Dental Sci. Kagoshima Jpn

• Takesue Tetsuo

  Department Of Pediatrics Faculty Of Medicine Kagoshima University

• Oku S

  Kagoshima Univ. Kagoshima Jpn

• Yamamoto Eiji

  Department of Applied Mathematics, Okayama University of Science

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