SERUM β2-MICROGLOBULIN LEVELS IN HEALTHY SUBJECTS AND PATIENTS WITH STOMACH CANCER

概要

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The serum β2-microglobulin was determined by a radioimmunoassay in 39 healthy subjects and 50 patients with stomach cancer admitted to our hospital for surgical resection. The average value of serum β2-microglobulin in 39 healthy subjects was 1.73±0.52 μg/ml. Even in early stage of stomach cancer the mean value was higher than that of healthy control. Except for early stomach cancer mean serum level of β2-microglobulin increased the progression of stomach cancer, though individual values distributed wide range. Serum levels seemed to be higher in a group of differentiated stomach cancers than that of undifferentiated stomach cancers, and also higher in male patients than in female ones. High postoperation value seemed to be poor prognostic marker especially in Stage IV. No obvious differences was found in the groups either with/without organ involvement or with/without shorter survival (within 12 months death).
財団法人日本消化器病学会の論文