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We have investigated the clinical meanings of CEA in 158 cases with primary cancer of large intestine and 33 cases of recurred cancer. The CEA positivity was 35 % in the primary cases and 82 % in recurred cases. This suggested the possibility to predict recurrences of cancer. A correlation could be noted between the stage classification and the CEA positivity, but no difference was found out between stage III and N. It was assumed that the pathological factors exerting influences upon the CEA positivity would be the diameters, degrees of penetration, and v-factor, but not n-factor and ly-factor. The progress in the CEA values thronghout 3 months after the operation could be used for evaluating the radical cure of the operation and predicting the prognosis. A possibility could be suggested that the prognosis of an operation can be made with the pre-operative CEA values. The CEA levels in liver metastasis were higher than those, in local recurrence and in dissemination, but in more than 20ng/ml liver metastasis showed multiple. It was difficult to diagnose the solitay hepatic metastasis by the CEA values. A correlation could be noted between the therapeutic difficacy by the chemotherapy and the progress in the CEA values.
日本大腸肛門病学会の論文