Clinical significance of PFD test and fecal chymotrypsin test in postoperative pancreatic exocrine insufficiency.

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Clinical significance of BT-PABA (PFD) test and fecal chymotrypsin test (FCT) in postoperative pancreatic exocrine insufficiency were examined.In cases whose D-xylose output in 5 grams D-xylose test were more than 1.2 grams, the correlation of urinary PABA excretion rate in PFD test and fecal chymotrypsin activity in FCT was significant. In cases whose D-xylose output were below 1.2 grams there was not significant. However, pancreatic maldigestive ratio (PMDR) which is a rate corrected PABA excretion rate with D-xylose output and chymotrypsin activity in FCT was significantly correlated in all cases.From these results we concluded that PFD test and FCT are useful in the evaluation of postoperative pancreatic exocrine function. And we propose to use D-xylose test concomitantly in PFD test to correct malabsorption of PABA.
財団法人日本消化器病学会の論文