α-,β-ナフタリンスルホン酸のイオン交換樹脂による分離定量

概要

論文の詳細を見る
Ion exchange resins have been used widely as a fixed phase in chromatography and the method described herein is an application of the molecular adsorption phenomenon. It is known that weak acids are adsorbed by the cation exchang resins. Also, naphthalenesulfonic acid in sodium chloride solution of pH below 4.0 is strongly adsorbed by weakly acidic cation exchange resin. The distribution coefficient is increased with an increase of the concentration of NaC1 and by lowering the pH value. For example, the distribution coefficient of the β-sulfonic acid was 70 and that of α-sulfonic acid was 30 in 4N NaCl and at pH 3.5. These were separated by elution at 40°C through an Amberlite CG-50 (200400 mesh) column of 11 mm ×225 mm with 4N NaCl of pH 3.30 as developer, and a satisfactory result was obtained. Although it was a difficult problem to make a quantitative separation of α- and β-naphthalenesulfonic acid, their separation became possible by application of the above method.
社団法人日本分析化学会の論文