A Case of Harada Disease with Hearing Loss

概要

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The patient was a 20-year-old man with the chief complaint of bilateral hearing loss following a cold with headache, fever and hyperemia of both eyes. Two weeks after the onset bilateral hearing loss and tinnitus appeared. Pure tone audiometry revealed moderate sensory neural hearing loss; the ABR wave V detection thres-hold was 60 dB HL in both ears in response to click stimuli at 3000Hz. No abnormal nystagmus was seen on ENG, Plain X-ray films and CT scans did not reveal any abnormality of the ears. Finally, Harada disease was diagnosed by fundoscopy.<BR>Auditory acuity was improved, except at 8000 Hz, within 6 days by steroid treatment. Two weeks were required for restoration to the normal level at 8000Hz.<BR>Inner ear function appeared to respond promptly to steroid treatment, but ophthalmological improvement was slow.<BR>Harada disease is considered to be an autoimmune disease against melanocytes, and it may cause endolymphatic hydrops.
日本めまい平衡医学会の論文